Evidence map›Paper›PMID 39850898›Full record

ArticleFrontiers in immunology2024

Synergistic defecation effects of

Qi Zhang, Wen Zhao, Jie Luo, Shaoqi Shi, Xiaokang Niu, Jian He, Yicheng Wang, Zhaozhong Zeng, Qiuyue Jiang, Bing Fang and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Foods (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Qi Zhang *Key Laboratory of Functional Dairy, Co-Constructed by Ministry of Education and Beijing Municipality, Department of Nutrition and Health, China Agricultural University, Beijing, China.
Wen Zhao *Key Laboratory of Functional Dairy, Co-Constructed by Ministry of Education and Beijing Municipality, Department of Nutrition and Health, China Agricultural University, Beijing, China.
Jie Luo *College of Food Science and Technology, Hunan Agricultural University, Changsha, China.
Shaoqi ShiKey Laboratory of Functional Dairy, Co-Constructed by Ministry of Education and Beijing Municipality, Department of Nutrition and Health, China Agricultural University, Beijing, China.
Xiaokang NiuKey Laboratory of Functional Dairy, Co-Constructed by Ministry of Education and Beijing Municipality, Department of Nutrition and Health, China Agricultural University, Beijing, China.
Jian HeProbiotics R&D Department, Inner Mongolia National Center of Technology Innovation for Dairy Co. Ltd., Hohhot, China.
Yicheng WangKey Laboratory of Functional Dairy, Co-Constructed by Ministry of Education and Beijing Municipality, Department of Nutrition and Health, China Agricultural University, Beijing, China.
Zhaozhong ZengProbiotics R&D Department, Inner Mongolia National Center of Technology Innovation for Dairy Co. Ltd., Hohhot, China.
Qiuyue JiangYili Innovation Center, Inner Mongolia Yili Industrial Group Co. Ltd., Hohhot, China.
Bing FangKey Laboratory of Functional Dairy, Co-Constructed by Ministry of Education and Beijing Municipality, Department of Nutrition and Health, China Agricultural University, Beijing, China.
Juan ChenKey Laboratory of Functional Dairy, Co-Constructed by Ministry of Education and Beijing Municipality, Department of Nutrition and Health, China Agricultural University, Beijing, China.
Yixuan LiKey Laboratory of Functional Dairy, Co-Constructed by Ministry of Education and Beijing Municipality, Department of Nutrition and Health, China Agricultural University, Beijing, China.
Fuqing WangDepartment of Food Science, Tibet Tianhong Science and Technology Co., Ltd., Lhasa, China.
Jingjing HeKey Laboratory of Functional Dairy, Co-Constructed by Ministry of Education and Beijing Municipality, Department of Nutrition and Health, China Agricultural University, Beijing, China.
Jie GuoKey Laboratory of Functional Dairy, Co-Constructed by Ministry of Education and Beijing Municipality, Department of Nutrition and Health, China Agricultural University, Beijing, China.
Ming ZhangSchool of Food and Chemical Engineering, Beijing Technology and Business University, Beijing, China.
Liwei ZhangKey Laboratory of Functional Dairy, Co-Constructed by Ministry of Education and Beijing Municipality, Department of Nutrition and Health, China Agricultural University, Beijing, China.
Shaoyang GeProbiotics R&D Department, Hebei Engineering Research Center of Animal Product, Sanhe, China.
Wei-Lian HungProbiotics R&D Department, Inner Mongolia National Center of Technology Innovation for Dairy Co. Ltd., Hohhot, China.
Ran WangKey Laboratory of Functional Dairy, Co-Constructed by Ministry of Education and Beijing Municipality, Department of Nutrition and Health, China Agricultural University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Synbiotics have revealed the possibility of improving constipation through gut microbiota. The synergistic efficacy of Methods: Loperamide-induced constipated mice model was established to explore the effect of BL-99, FOS, and BL-99+FOS on changes of defecation-related parameters, gut microbiota and metabolites. Results and discussion: The results showed that BL-99, FOS, and BL-99+FOS each alleviated constipation, with the synbiotic showing significant efficacy in the first black stool defecation time, fecal number, fecal weight, and the gastrointestinal transit rate (

Indexed as

Bifidobacterium animalisConstipationDefecationGastrointestinal MicrobiomeOligosaccharidesSynbioticsAnimalsDisease Models, AnimalFecesMaleMiceProbioticsfructooligosaccharideOligosaccharidesBifidobacterium animalis subsp. lactis BL-99constipationfructooligosaccharidegut microbiotaserum inflammatory factors

Identifiers

PMID39850898
PMCPMC11754280

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.