Evidence map›Paper›PMID 39850797›Full record

ArticleBMJ neurology open2025

Diffusion tensor imaging in peroneal neuropathy: a prospective, single-centre study.

Christophe Oosterbos, Ahmed M Radwan, Stefan Sunaert, Sophie Hoornaert, Anais Van Hoylandt, Robin Lemmens, Tom Theys

Abstract read
In one paragraph

Article in BMJ neurology open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Christophe Oosterbos *Neurosurgery, Ziekenhuis Oost-Limburg Campus Sint-Jan, Genk, Belgium.ORCID 0000-0003-2142-9941
Ahmed M Radwan *Imaging and Pathology, Translational MRI, KU Leuven, Leuven, Belgium.ORCID 0000-0002-4819-548X
Stefan SunaertRadiology, UZ Leuven, Leuven, Belgium.
Sophie HoornaertResearch Group experimental Neurosurgery and Neuroanatomy and the Leuven Brain Institute, KU Leuven, Leuven, Flanders, Belgium.
Anais Van HoylandtResearch Group experimental Neurosurgery and Neuroanatomy and the Leuven Brain Institute, KU Leuven, Leuven, Flanders, Belgium.
Robin LemmensNeurology, University Hospitals Leuven, Leuven, Belgium.ORCID 0000-0002-4948-5956
Tom TheysResearch Group experimental Neurosurgery and Neuroanatomy and the Leuven Brain Institute, KU Leuven, Leuven, Flanders, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Diffusion tensor imaging (DTI) showed promising results in diagnosing upper limb neuropathies, but its value in patients with foot drop due to peroneal neuropathy has not yet been investigated. We aim to establish reference values for DTI metrics of the healthy peroneal nerve and to evaluate differences in DTI metrics between patients and healthy controls. Methods: Diffusion-weighted images (DWI) from 22 pathological nerves, 14 asymptomatic patients' nerves and 65 healthy peroneal nerves were processed for quantitative assessment of fractional anisotropy (FA), radial diffusivity (RD), axial diffusivity and mean diffusivity. Clinical baseline and follow-up data were prospectively collected for all patients. Results: Mean patient FA values (0.40, SD 0.08) were significantly lower compared with healthy controls (mean FA 0.44, SD 0.06). Mean patient RD values (0.98 10 Conclusion: Based on these results, DTI appears to aid in the differential diagnostic process of patients with peroneal neuropathy. Future studies should focus on automation of DWI processing, confirm the results in larger patient groups and try to establish reliable cut-off values for DTI metrics.

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MRINEUROPATHY

Identifiers

PMID39850797
PMCPMC11751924

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