Evidence map›Paper›PMID 39850661›Full record

ArticleToxicology research2025

Comprehensive evaluation of the toxicological effects of commonly encountered synthetic cathinones using in silico methods.

Can Özgür Yalçın, Sezen Yılmaz Sarıaltın, Giuseppa Raitano, Emilio Benfenati

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Can Özgür YalçınDepartment of Pharmaceutical Toxicology, Karadeniz Technical University Faculty of Pharmacy, Trabzon, Türkiye.ORCID https://orcid.org/0000-0003-4032-3229
Sezen Yılmaz SarıaltınDepartment of Pharmaceutical Toxicology, Ankara University Faculty of Pharmacy, Ankara, Türkiye.
Giuseppa RaitanoDepartment of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Emilio BenfenatiDepartment of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthetic cathinones (SCs), a group of new psychoactive substances (NPS), are designer molecules with hallucinogenic and psychostimulatory effects. Although the structural similarities of SCs to amphetamines suggest that they may have similar toxicity profiles to those of amphetamine congeners, little is known about SCs from a toxicological point of view. In the present study, the toxicity profiles of commonly encountered SCs (

Indexed as

acute toxicityADMETcarcinogenicityGenotoxicityIn silicosynthetic cathinones

Identifiers

PMID39850661
PMCPMC11751583

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.