ArticleJOR spine2025
Is There a Positive or Negative Correlation Between Cervical Vertebral Bone Quality and Intervertebral Disc Degeneration by Pfirrmann Grading.
Article in JOR spine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Comparison of the predictive value of mri-based cervical endplate bone quality (C-EBQ) score and cervical vertebral bone quality (C-VBQ) score for the progression of cervical disc degeneration.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- The predictive value of MRI-based vertebral bone quality score for adjacent segment degeneration following single-level anterior cervical fusion.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
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Authors and funding
10 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Objective: Cervical degeneration involves many pathophysiological changes. Vertebral bone loss, sclerotic hyperplasia of the vertebral body and intervertebral disc degeneration (IDD) are most common degenerative factors. However, whether there is a correlation between changes in vertebral bone mass and IDD remains unclear. In this study, based on magnetic resonance imaging (MRI), Pfirrmann method was used to grade cervical disc degeneration, and vertebral bone quality (VBQ) was measured. The correlation between VBQ and IDD was analyzed, and its potential mechanism was discussed as well. Methods: From June 2019 to June 2023, clinical data of patients undergoing surgical treatment for cervical degenerative disc diseases (CDDD) in our department were retrospectively analyzed. Preoperative MRI was collected, the degree of IDD was assessed by Pfirrmann grading, and VBQ was measured by T1-weighted image of MRI. With VBQ score = 3.08 as the threshold, Spearman correlation analysis was used to quantified the correlation between IDD grade and VBQ, and multiple ordered Logistic regression analysis was used to evaluate the effect of VBQ on IDD grade. Results: The preoperative MRI data of 94 patients (male, 42; female, 52) with CDDD were collected. Spearman correlation analysis: When VBQ score ≤ 3.08, the IDD grade was negatively correlated with VBQ ( Conclusions: Either excessive increased or decreased VBQ in the cervical spine may accelerate the progression of IDD. The reason may be that both abnormal interference from the VBQ may imbalance the cervical spinal biomechanics and compromise the absorption of nutrients in the disc, thus accelerating the IDD. Therefore, cervical VBQ may have a bidirectional effect on IDD.
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