Evidence map›Paper›PMID 39850469›Full record

ArticleFrontiers in oral health2024

Periodontal pathogens and obesity in the context of cardiovascular risks across age groups.

Georgy Leonov, Yurgita Varaeva, Elena Livantsova, Andrey Vasilyev, Olga Vladimirskaya, Tatyana Korotkova, Dmitry Nikityuk, Antonina Starodubova

Abstract read
In one paragraph

Article in Frontiers in oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Journal of oral microbiology · 2026
    Review
  4. Review
  5. Microbial dysbiosis in oral cavity determines obesity status in adolescents.Cellular and molecular life sciences : CMLS · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Oral microbiota in cardiovascular health and disease.Frontiers in cellular and infection microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Georgy LeonovDepartment of Cardiovascular Pathology and Diet Therapy, Federal Research Centre for Nutrition, Biotechnology and Food Safety, Moscow, Russia.
Yurgita VaraevaDepartment of Cardiovascular Pathology and Diet Therapy, Federal Research Centre for Nutrition, Biotechnology and Food Safety, Moscow, Russia.
Elena LivantsovaDepartment of Cardiovascular Pathology and Diet Therapy, Federal Research Centre for Nutrition, Biotechnology and Food Safety, Moscow, Russia.
Andrey VasilyevDepartment of Microbiology, Central Research Institute of Dental and Maxillofacial Surgery, Moscow, Russia.
Olga VladimirskayaDepartment of Microbiology, Central Research Institute of Dental and Maxillofacial Surgery, Moscow, Russia.
Tatyana KorotkovaDepartment of Cardiovascular Pathology and Diet Therapy, Federal Research Centre for Nutrition, Biotechnology and Food Safety, Moscow, Russia.
Dmitry NikityukDepartment of Cardiovascular Pathology and Diet Therapy, Federal Research Centre for Nutrition, Biotechnology and Food Safety, Moscow, Russia.
Antonina StarodubovaDepartment of Cardiovascular Pathology and Diet Therapy, Federal Research Centre for Nutrition, Biotechnology and Food Safety, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiovascular diseases (CVDs) are the leading cause of mortality and morbidity among noncommunicable diseases. Over the past decade, there has been a notable increase in the prevalence of CVDs among young individuals. Obesity, a well-known risk factor for CVDs, is also associated with various comorbidities that may contribute to cardiovascular risk. The relationship between periodontal pathogens and CVD risk factors, including obesity, smoking, lipid metabolism disorders, and inflammatory markers, remains underexplored. Methods: This study examined the relationship between six periodontal pathogens ( Results: The prevalence of periodontal pathogens in the population was 33.0% for Conclusions: This study highlights the potential connection between periodontal pathogens and risk factors associated with cardiovascular disease, including smoking, elevated BMI, increased adipose tissue, hypertension, and dyslipidemia. Further research is required to determine the causal relationships between oral microbiome dysbiosis, obesity and, systemic diseases and to develop an effective strategy for preventing oral health-related CVD risk factors in young adults.

Indexed as

biomarkerscardiovascular diseaseobesityperiodontal pathogensP. gingivalis

Identifiers

PMID39850469
PMCPMC11754283

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.