ArticleFrontiers in cardiovascular medicine2024
Impact of high hemoglobin levels on carotid artery intima-media thickness and its predictive value for hypertension in high-altitude areas: a real-world study.
Article in Frontiers in cardiovascular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Excessive erythrocytosis and the hypertensive phenotype at high altitude: emerging evidence and unresolved questions.Frontiers in cardiovascular medicine · 2026Review
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7 authors.
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Abstract
Background and purpose: The hemoglobin levels in the peripheral blood of individuals living at high altitudes are significantly higher than normal levels. These levels are closely associated with atherosclerosis and cardiovascular events. This study aimed to investigate the correlation between hemoglobin levels in the peripheral blood and hypertension in high-altitude regions, providing a basis for preventing and treating primary hypertension in these regions. Materials and methods: From May 2020 to May 2021, patients diagnosed with primary hypertension in plateau regions of China were selected as participants. The clinical data, including lifestyle habits and blood biochemical indicators, were collected from the clinical case database for patients meeting the inclusion criteria. The logistic regression analysis was performed to identify factors influencing carotid intima-media thickness in patients with primary hypertension in plateau regions. The ROC curve was plotted to analyze the impact of peripheral blood hemoglobin levels on hypertension, determine the hemoglobin threshold for predicting hypertension in plateau areas, and evaluate the predictive value of hemoglobin level for hypertension. Results: A total of 200 patients (105 men with an average age of 64.8 ± 12.75 years and 95 women with an average age of 69.5 ± 11.54 years) were enrolled in this study. Logistic regression analysis revealed that age, CO Conclusion: Elevated hemoglobin levels contribute to the thickening of the carotid artery intima-media layer and hold predictive value for high-altitude hypertension.
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