ArticleCureus2024
A Pilot Case-Control Study of Muscle and Bone Health Status in Patients Who Have Recovered From COVID-19 Infection.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Multiscale bone remodeling in COVID-19: from osteoimmune signaling to structural and mechanical impairment.Frontiers in bioengineering and biotechnology · 2026Review
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCoronavirus disease 2019 (COVID-19), resulting from the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), affects various bodily systems, including the heart, central nervous system, muscles, and bones, all of which harbor angiotensin-converting enzyme 2 (ACE-2) receptors similar to those in the respiratory system. However, research on the inflammatory response and its impact on systems such as the musculoskeletal one is relatively scarce. Our study aimed to investigate bone and muscle metrics as well as handgrip strength in individuals who recuperated from COVID-19 infection.
methodsThe pilot case-control study was conducted from June 2021 to September 2022, involving 25 adult patients aged 18-60 years who had recovered from COVID-19 infection, alongside 25 age- and gender-matched controls. Participants were recruited from a tertiary care hospital in Pune, and data on demographics, anthropometry, medical history, diet, and physical activity were recorded using standardized questionnaires. Dual-energy X-ray absorptiometry (DXA) and peripheral quantitative computed tomography (pQCT) were used to assess bone and muscle parameters, whereas a handgrip dynamometer was used to measure muscle strength. Statistical analysis was performed using SPSS version 26.0 (IBM Corp., Armonk, NY).
resultsPost-COVID-19 recovered female patients exhibited lower lean mass, muscle density, and handgrip strength, alongside higher body fat levels.
conclusionLean mass, muscle density, and handgrip strength were lower and body fat was higher in post-COVID-19 recovered females, thus indicating the need to focus on improving the musculoskeletal health of females post-hospitalization due to a serious illness such as COVID-19 infection.
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