ArticleIranian journal of basic medical sciences2025
Hydroxytyrosol protects isoproterenol-induced myocardial infarction through activating notch signaling.
Article in Iranian journal of basic medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Cuminaldehyde, a natural monocyclic terpenoid, attenuates isoproterenol-induced myocardial infarction in rats via modulation of Bax/Bcl-2/Bcl-xL/Cyt.c/caspase- 9/caspase-3, and MMP-2/MMP-9 pathways.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Single-Cell Transcriptomics of Human Acute Myocardial Infarction Reveals Oxidative Stress-Associated Cardiomyocyte Subpopulations and Candidate Predictive Signatures.Antioxidants (Basel, Switzerland) · 2025Article
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Authors and funding
8 authors.
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Abstract
Objectives: In this investigation, the protective effects of hydroxytyrosol (HT) administered prior to myocardial infarction in rats were examined, with a particular focus on its potential roles within the Notch pathway. Materials and Methods: The animals were categorized into seven groups (n=7): control, myocardial infarction (MI) 6 Results: The study revealed an increase in Notch1 and DLL4 levels, particularly at the 24 Conclusion: HT is thought to exert a cardioprotective effect in MI, potentially mediated through the Notch pathway.
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