SynthesisThe Journal of antimicrobial chemotherapy2025
Vancomycin-resistant Enterococcus prevalence and its association along the food chain: a systematic review and meta-analysis.
Synthesis in The Journal of antimicrobial chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- The Role of Postbiotics in Poultry Health and Performance: A Review on Existing Knowledge and Further Research Needs.International journal of molecular sciences · 2026Review
- Vancomycin-Resistant, ThermotolerantFoods (Basel, Switzerland) · 2026Article
- Novel Insights into Metagenomic-Assembled Genomes from Layer Chicken Housing Environment.International journal of molecular sciences · 2026Article
- Antimicrobial resistance characteristics of enterococcus and analysis of intra-farm transmission associations in large-scale laying hen production.Poultry science · 2026Article
- Review
- Transmission and Evolution of Antibiotic Resistance Genes and Antibiotic-Resistant Bacteria in Animals, Food, Humans and the Environment.Microorganisms · 2026Review
- Integrated Phenotypic and Genomic Profiling of Antimicrobial Resistance and Virulence-Associated Determinants in Poultry-DerivedVeterinary sciences · 2026Article
- Prevalence and Antimicrobial Resistance Profiles of Enterococci Isolated From Humans, Animals, and Environment in Bangladesh: A Systematic Review and Meta-Analysis.International journal of microbiology · 2026Review
- Article
- Mobilome-driven antimicrobial resistance in a one health context: evidence and lessons from Africa.Frontiers in veterinary science · 2026Review
- Species-aware interpretation of vancomycin-related genomic signals in poultry-derivedFrontiers in veterinary science · 2026Article
- Prevalence of Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2025Article
- Vancomycin-ResistantMicroorganisms · 2025Article
- Does Bovine Raw Milk Represent a Potential Risk for Vancomycin-Resistant Enterococci (VRE) Transmission to Humans?Antibiotics (Basel, Switzerland) · 2025Article
- Antibiotic Resistance in the Philippines: Environmental Reservoirs, Spillovers, and One-Health Research Gaps.Frontiers in microbiology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundVancomycin-resistant Enterococcus (VRE) are present across the One Health continuum and pose a considerable risk for transmission along the food chain. This systematic review and meta-analysis estimates the prevalence of VRE colonization in livestock, food of animal origin, and in human populations.
methodsEmbase, MEDLINE and CAB Abstracts were searched for eligible literature. A total of 54 manuscripts passed inclusion criteria by providing prevalence estimates of VRE in a human population and at least one of either livestock or food. Random effects meta-analysis was conducted to determine prevalence estimates, and risk of bias in pooled estimates was assessed using funnel plots and Egger regression.
resultsGlobal pooled prevalence of VRE colonization was highest in poultry and poultry meat at 16% (95% CI: 6%-28%) and 15% (95% CI: 1%-39%), respectively. Human-associated VRE colonization was highest in livestock workers, with a pooled prevalence of 11% (95% CI: 2%-25%), and lowest in the general public at 2% (95% CI: 0%-3%). Meta-regression demonstrated that human VRE prevalence increased at a rate of 0.75% (95% CI: 0.46%-1.04%; P < 0.001) per 1% increase in livestock VRE colonization.
conclusionsThis meta-analysis established a clear link of VRE across One Health sectors. VRE colonization is likely elevated for those in contact with colonized animals or contaminated food products. Quality of evidence in pooled prevalence estimates was limited by publication bias and heterogeneity. The results of this study enhance calls for a One Health approach for mitigating the global burden of priority antimicrobial resistance pathogens.
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