Evidence map›Paper›PMID 39849814›Full record

ArticleThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi2025

Microangiopathic Hemolytic Anemia: A Rare Complication of Acute Pancreatitis.

Syedda Ayesha, Masood Muhammad Karim, Maria Ali, Abdul Hadi Shahid, Salman Naseem Adil

Abstract readCase Reports
In one paragraph

Article in The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Syedda AyeshaSection of Gastroenterology, Department of Medicine, Aga Khan University, Karachi, Pakistan.ORCID 0009-0007-4893-3335
Masood Muhammad KarimSection of Gastroenterology, Department of Medicine, Aga Khan University, Karachi, Pakistan.
Maria AliSection of Haematology, Department of Pathology and Laboratory Medicine, Aga Khan University, Karachi, Pakistan.
Abdul Hadi ShahidMedical college, Aga Khan University, Karachi, Pakistan.
Salman Naseem AdilSection of Haematology, Department of Pathology and Laboratory Medicine, Aga Khan University, Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microangiopathic hemolytic anemia (MAHA) is a rare subtype of hemolytic anemia characterized by elevated hemolytic markers and red blood cell destruction. Though uncommon, MAHA can occur as a complication of acute pancreatitis because of the associated inflammatory response. Patients with MAHA secondary to pancreatitis show favorable outcomes when treated with plasma exchange. This paper presents the case of a patient diagnosed with acute pancreatitis-induced hemolytic anemia and thrombocytopenia, who was managed successfully with plasma exchange, steroids, and rituximab. Clinicians should maintain a high index of suspicion in patients with acute pancreatitis who present with anemia, thrombocytopenia, and schistocytes on peripheral smears, even in the absence of end-organ injuries and with normal ADAMTS13 activity. The early initiation of plasmapheresis can be lifesaving. The timely introduction of rituximab in cases where plasma exchange and steroids are insufficient, despite the ADAMTS13 activity status, may lead to better outcomes.

Indexed as

Anemia, HemolyticPancreatitisThrombocytopeniaADAMTS13 ProteinHumansPlasma ExchangePlasmapheresisRituximabSteroidsTomography, X-Ray ComputedADAMTS13 ProteinADAMTS13 protein, humanRituximabSteroidsMicroangiopathic hemolytic anemiaPancreatitisPlasmapheresisRituximabThrombocytopenia

Identifiers

PMID39849814
PMCPMC12285422

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.