Evidence map›Paper›PMID 39849598›Full record

ArticleBMC research notes2025

Remodeling the light-adapted electroretinogram using a bayesian statistical approach.

Marek Brabec, Fernando Marmolejo-Ramos, Lynne Loh, Irene O Lee, Mikhail Kulyabin, Aleksei Zhdanov, Hugo Posada-Quintero, Dorothy A Thompson, Paul A Constable

Abstract read
In one paragraph

Article in BMC research notes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marek BrabecInstitute of Computer Science, Czech Academy of Sciences, Pod Vodarenskou Vezi 2, Prague 8, 182 00, Czech Republic.ORCID http://orcid.org/0000-0001-6367-5791
Fernando Marmolejo-RamosCollege of Education, Psychology, and Social Work, Flinders University, Adelaide, Australia.ORCID http://orcid.org/0000-0003-4680-1287
Lynne LohCollege of Nursing and Health Sciences, Flinders University, Caring Futures Institute, Adelaide, Australia.ORCID http://orcid.org/0000-0002-1357-9395
Irene O LeeBehavioural and Brain Sciences Unit, Population Policy and Practice Programme, Great Ormond Street Institute of Child Health, University College London, University College London, London, UK.ORCID http://orcid.org/0000-0003-0004-6802
Mikhail KulyabinPattern Recognition Lab, Department of Computer Science, Friedrich-Alexander-Universitat Erlangen-Nurnberg, 91058, Erlangen, Germany.ORCID http://orcid.org/0009-0007-0440-030X
Aleksei ZhdanovVisioMed.AI, Moscow, Russia.ORCID http://orcid.org/0000-0003-4725-3681
Hugo Posada-QuinteroBiomedical Engineering Department, University of Connecticut, Storrs, CT, 06269, USA.ORCID http://orcid.org/0000-0003-4514-4772
Dorothy A ThompsonTony Kriss Visual Electrophysiology Unit, Clinical and Academic Department of Ophthalmology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.ORCID http://orcid.org/0000-0001-5491-3911
Paul A ConstableCollege of Nursing and Health Sciences, Flinders University, Caring Futures Institute, Adelaide, Australia. Paul.constable@flinders.edu.au.ORCID http://orcid.org/0000-0002-3994-1700

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo present a remodeling of the electroretinogram waveform using a covariance matrix to identify regions of interest and distinction between a control and attention deficit/hyperactivity disorder (ADHD) group. Electroretinograms were recorded in n = 25 ADHD (16 male; age 11.9 ± 2.7 years) and n = 38 (8 male; age 10.4 ± 2.8 years neurotypical control participants as part of a broad study into the determining if the electroretinogram could be a biomarker for ADHD. Flash strengths of 0.6 and 1.2 log cd.s.m

resultsThe correlation matrices indicated less correlation within the waveforms for the ADHD group in time intervals beyond 70 msec. The eigenvalue plots suggest more complexity within the ADHD group compared to the control group. Consideration of the correlation structure between ERG waveforms from different populations may reveal additional features for identifying group differences in clinical populations.

Indexed as

Attention Deficit Disorder with HyperactivityElectroretinographyLightRetinaAdolescentBayes TheoremCase-Control StudiesChildFemaleHumansMalePhotic StimulationAttention deficit hyperactivity disorderNeurodevelopmentRetinaTime-domain ERG trajectory

Identifiers

PMID39849598
PMCPMC11760095

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.