ArticleBMC oral health2025
Clinical outcome and volumetric 3D analysis of biofluorescence imaging system guided surgery for Medication-Related Osteonecrosis of the Jaw(MRONJ).
Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Autologous Platelet Concentrates in the Management of Medication-Related Osteonecrosis of the Jaw: A Systematic Review.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Polydeoxyribonucleotide (PDRN) in Dentistry: Narrative Review for Mechanisms and Emerging Clinical Applications.Tissue engineering and regenerative medicine · 2026Review
- Biofluorescence imaging-guided implantoplasty for the management of peri-implantitis: a retrospective case series.BMC oral health · 2026Article
- A scientometric study on research trends and characteristics of medication-related osteonecrosis of the jaw.Journal of dental sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundThis study aims to evaluate the clinical outcome of biofluorescent imaging system (BIS) guided MRONJ surgery through analyzing 3D volumetric changes in CBCT data of bone structure.
methodsBIS-guided surgery for MRONJ surgery was performed by grinding red-fluorescent area from remained residual bone detected by Qray-pen. CBCT data was collected preoperatively, postoperatively, and at last follow-up more than 3 months of each patient. Healing ratio per month was calculated through measuring difference between postoperative defect and last follow-up defect volume by analyzing CBCT.
resultsWith mean follow-up period of 7.8 ± 4.8 months, twelve MRONJ surgeries of 11 patients (2 males, 9 females, mean 72.8 ± 13.7 years old) showed bone healing tendency without recurrence in average healing ratio of 5.49 ± 2.22% per month, with complete soft tissue closure. It was observed that the healing ratio per month did not show statistically significant differences based on location of MRONJ, size of post-operative defect volume, nor duration of bisphosphonate intake before surgery.
conclusionsBased on three-dimensional bone analysis, efficacy of BIS-based MRONJ surgery was proved through the recovery pattern of underlying bone structure and no recurrence sign showing. CLINICAL
trial registrationNot applicable.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.