Evidence map›Paper›PMID 39849413›Full record

ArticleBMC pulmonary medicine2025

Association between dietary intake of live microbes and chronic obstructive pulmonary disease: a cross-sectional study of NHANES 2007-2012.

Yifeng Xu, Zhaoqi Yan, Liangji Liu

Registry-linked trialAbstract read
In one paragraph

Article in BMC pulmonary medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00005154 (National Health and Nutrition Examination Survey IV), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00005154 completednot on this map

National Health and Nutrition Examination Survey IV (NHANES (IV)

TypeobservationalSponsorNational Heart, Lung, and Blood Institute (NHLBI)Ran1981 to 2008ConditionsCardiovascular Diseases, Coronary Disease, Heart Diseases, Hypertension
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yifeng XuSchool of Clinical Medicine, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.
Zhaoqi YanSchool of Clinical Medicine, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.
Liangji LiuAffiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China. llj6505@163.com.

Funding

Jiangxi Clinical Medical Research Center of Lung Diseases Gan ke fa she [2019] No. 44Jiangxi University of Chinese Medicine Science and Technology Innovation Team Development Program No. CXTD22011
6 · The paper itself

Abstract

backgroundDiet plays a crucial role in intervening in the development of chronic obstructive pulmonary disease (COPD), yet previous studies have not investigated the impact of dietary intake of live microbes on COPD. This study aims to assess the relationship between the two.

methodsParticipants from the National Health and Nutrition Examination Survey (NHANES) from 2007 to 2012 were selected. The exposure variable was the estimated intake of live microbes in the diet, categorized into low, medium, and high groups. The outcome variable was COPD. A multivariable logistic regression model was used to assess the relationship between estimated dietary intake of live microbes and the risk of COPD.

resultsIn the fully adjusted multiple logistic regression model, participants with moderate and high dietary intake of live microbes showed a negative association with the prevalence of COPD compared to those with low estimated intake, with reductions of 38% (OR, 0.62; 95% CI: 0.39-0.99, P < 0.05) and 44% (OR, 0.56; 95% CI: 0.34-0.92, P < 0.05) respectively. Additionally, subgroup analysis results remained stable with no observed interactions.

conclusionOur study suggests a negative association between higher dietary live microbe intake and the risk of COPD among adults in the United States.

trial registrationClinicalTrials.gov Identifier NCT00005154 First Posted date 26/05/2000(retrospectively registered).

Indexed as

DietPulmonary Disease, Chronic ObstructiveAdultAgedCross-Sectional StudiesFemaleHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisNutrition SurveysPrevalenceRisk FactorsUnited StatesCOPDCross-sectional studyGut-lung axisLive microbesNHANES

Identifiers

PMID39849413
PMCPMC11760668

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Registered trials

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