ArticleBMC cardiovascular disorders2025
Feasibility analysis of non-electrocardiogram-triggered chest low-dose computed tomography using a kV-independent reconstruction algorithm for predicting cardiovascular disease risk in patients receiving maintenance hemodialysis.
Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesThis study aimed to evaluate the feasibility and accuracy of non-electrocardiogram (ECG)-triggered chest low-dose computed tomography (LDCT) with a kV-independent reconstruction algorithm in assessing coronary artery calcification (CAC) degree and cardiovascular disease risk in patients receiving maintenance hemodialysis (MHD).
methodsIn total, 181 patients receiving MHD who needed chest CT and coronary artery calcium score (CACS) scannings sequentially underwent non-ECG-triggered, automated tube voltage selection, high-pitch chest LDCT with a kV-independent reconstruction algorithm and ECG-triggered standard CACS scannings. Then, the image quality, radiation doses, Agatston scores (ASs), and cardiac risk classifications of the two scans were compared.
resultsOf the 181 patients, 89, 83, and 9 were scanned at 100, 110, and 120 kV, respectively. Excluding those scanned at 120 kV, 172 patients were enrolled. Although the ASs of non-ECG-triggered LDCT were lower than those of the standard CACS, the agreement and correlation of ASs of the two scans were excellent, and both intraclass correlation coefficients (ICCs) and Pearson's correlation coefficients were > 0.96. Cardiac risk classifications did not significantly differ between the non-ECG-triggered LDCT and standard CACS (χ
conclusionsThe non-ECG-triggered, automated tube voltage selection, high-pitch chest LDCT protocol with a kV-independent reconstruction algorithm can obtain chest scans and ASs simultaneously and significantly reduce patients' radiation exposure.
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