Evidence map›Paper›PMID 39849360›Full record

ArticleBMC bioinformatics2025

BAC-browser: the tool for synthetic biology.

Tatiana A Semashko, Gleb Y Fisunov, Georgiy Y Shevelev, Vadim M Govorun

Abstract read
In one paragraph

Article in BMC bioinformatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Genomic surveillance of the pneumonia outbreak caused byFrontiers in cellular and infection microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tatiana A SemashkoResearch Institute for Systems Biology and Medicine, Moscow, Russian Federation. t.semashko@gmail.com.
Gleb Y FisunovResearch Institute for Systems Biology and Medicine, Moscow, Russian Federation.
Georgiy Y ShevelevInstitute of Chemical Biology and Fundamental Medicine, Novosibirsk, Russian Federation.
Vadim M GovorunResearch Institute for Systems Biology and Medicine, Moscow, Russian Federation.

Funding

Federal Service for Surveillance on Consumer Rights Protection 122030900107-3Russian Foundation for Basic Research 18-29-08043
6 · The paper itself

Abstract

backgroundCurrently, synthetic genomics is a rapidly developing field. Its main tasks, such as the design of synthetic sequences and the assembly of DNA sequences from synthetic oligonucleotides, require specialized software. In this article, we present a program with a graphical interface that allows non-bioinformatics to perform the tasks needed in synthetic genomics.

resultsWe developed BAC-browser v.2.1. It helps to design nucleotide sequences and features the following tools: generate nucleotide sequence from amino acid sequences using a codon frequency table for a specific organism, as well as visualization of restriction sites, GC composition, GC skew and secondary structure. To assemble DNA sequences, a fragmentation tool was created: regular breakdown into oligonucleotides of a certain length and breakdown into oligonucleotides with thermodynamic alignment. We demonstrate the possibility of DNA fragments assemblies designed in different modes of BAC-browser.

conclusionsThe BAC-browser has a large number of tools for working in the field of systemic genomics and is freely available at the link with a direct link https://sysbiomed.ru/upload/BAC-browser-2.1.zip .

Indexed as

Chromosomes, Artificial, BacterialGenomicsSoftwareSynthetic BiologyBase SequenceDNASequence Analysis, DNADNAGenome browserLCR assemblyPCR assemblySequence editorSynthetic biologySynthetic genomics

Identifiers

PMID39849360
PMCPMC11758742

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.