Evidence map›Paper›PMID 39849276›Full record

ArticleMolecular neurobiology2025

Ursonic Acid Ameliorates H

Jiahui Wang, Jia Yang, Jia Lu, Jingshi Lu, Bai Ling, Yan Song, Guangtong Chen

Abstract read
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In one paragraph

Article in Molecular neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiahui WangSchool of Pharmacy, Nantong University, 19 Qixiu Road, Nantong, 226001, People's Republic of China.
Jia YangSchool of Pharmacy, Nantong University, 19 Qixiu Road, Nantong, 226001, People's Republic of China.
Jia LuSchool of Pharmacy, Nantong University, 19 Qixiu Road, Nantong, 226001, People's Republic of China.
Jingshi LuSchool of Pharmacy, Nantong University, 19 Qixiu Road, Nantong, 226001, People's Republic of China.
Bai LingDepartment of Pharmacy, The Fourth Affiliated Hospital of Nantong University, Yancheng, China.
Yan SongSchool of Pharmacy, Nantong University, 19 Qixiu Road, Nantong, 226001, People's Republic of China. violet200599@ntu.edu.cn.
Guangtong ChenSchool of Pharmacy, Nantong University, 19 Qixiu Road, Nantong, 226001, People's Republic of China. guangtong_chen@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growing evidence suggests that plant compounds are emerging as a tremendous source for slowing the onset and progression of Alzheimer's disease (AD). Ursonic acid (UNA) is a naturally occurring pentacyclic triterpenoid with some hypoglycemic, anticancer, and antiinflammatory activities. However, the pharmacological effects of UNA on AD are still unknown. In the present experiments, the effects and mechanisms of UNA on AD were firstly explored by H

Indexed as

Caenorhabditis elegansHeme Oxygenase-1Hydrogen PeroxideLongevityMAP Kinase Signaling SystemNF-E2-Related Factor 2Oxidative StressSignal TransductionTriterpenesAmyloid beta-PeptidesAnimalsApoptosisCaenorhabditis elegans ProteinsCell SurvivalMembrane Potential, MitochondrialMitogen-Activated Protein KinasesAmyloid beta-PeptidesCaenorhabditis elegans ProteinsHeme Oxygenase-1Hydrogen PeroxideMitogen-Activated Protein KinasesNF-E2-Related Factor 2Reactive Oxygen SpeciesTriterpenesAlzheimer’s diseaseAntioxidantApoptosisMAPKs/Nrf2/HO-1 signaling pathwayUrsonic acid

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.