Evidence map›Paper›PMID 39849238›Full record

ArticleMolecular diversity2025

Synthesis and biological evaluation of rationally designed pyrazoles as insecticidal agents.

Aroog Fatima, Samina Aslam, Sara Janiad, Shah Faisal, Ali Irfan, Javed Iqbal, Gamal A Shazly, Ansa Madeeha Zafar, Aqeela Shaheen, Sobia Noreen and 2 more

Abstract read
In one paragraph

Article in Molecular diversity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Chemotyping ofPlants (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Aroog FatimaDepartment of Chemistry, The Women University Multan, Multan, 2023, Pakistan.
Samina AslamDepartment of Chemistry, The Women University Multan, Multan, 2023, Pakistan. drsamina.chem@wum.edu.pk.
Sara JaniadDepartment of Microbiology and Molecular Genetics, The Women University Multan, Multan, 2023, Pakistan.
Shah FaisalDepartment of Chemistry, Islamia College University Peshawar, Peshawar, 25120, Pakistan.
Ali IrfanDepartment of Chemistry, Government College University Faisalabad, Faisalabad, 38000, Pakistan. raialiirfan@gmail.com.
Javed IqbalDepartment of Agricultural Engineering, Khwaja Fareed University of Engineering and Information Technology (KFUEIT), Rahim Yar Khan, 64200, Pakistan.
Gamal A ShazlyDepartment of Pharmaceutics, College of Pharmacy, King Saud University, 11451, Riyadh, Saudi Arabia.
Ansa Madeeha ZafarDepartment of Chemistry, Government Sadiq College Women University, Bahawalpur, 63100, Pakistan.
Aqeela ShaheenDepartment of Chemistry, Government Sadiq College Women University, Bahawalpur, 63100, Pakistan.
Sobia NoreenInstitute of Chemistry, University of Sargodha, Sargodha, 40100, Pakistan.
Emilio MateevDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University, Sofia, Bulgaria.
Yousef A Bin JardanDepartment of Pharmaceutics, College of Pharmacy, King Saud University, 11451, Riyadh, Saudi Arabia. ybinjardan@ksu.edu.sa.

Funding

King Saud University RSPD2025R1118
6 · The paper itself

Abstract

The current research focused on the synthesis of two series of pyrazole derivatives and evaluation of their insecticidal effectiveness. In the first series, seven pyrazole Schiff bases 3a-g were successfully synthesized with yields (79-95%) by condensing phenylfuran-2-carbaldehyde with substituted pyrazole rings. In the second series, eleven amino acid-pyrazole conjugates 6a-k were synthesized utilizing acetic acid, sulfuric acid, morpholine, and EDC. HCl achieving yields of 59% to 94%. The synthesized compounds were assessed for their chemotherapeutic efficacy against locusts and termites by calculating LC

Indexed as

Drug DesignInsecticidesPyrazolesAnimalsIsopteraMolecular Docking SimulationStructure-Activity RelationshipInsecticidesPyrazolesAnti-locustAnti-termiteAryl pyrazolesFipronilMolecular dockingSchiff bases

Identifiers

PMID39849238
PMCPMC12638334

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.