Evidence map›Paper›PMID 39849187›Full record

Trial reportClinical oral investigations2025

Adjunctive therapea - a promising method in the treatment of periodontal disease.

Viktoria Margaryan, Eduard Aghasyan, Lazar Yessayan, Hakob Khachatryan, Curd Bollen, Gagik Hakobyan

RetractedAbstract readRandomized Controlled TrialRetracted Publication
PubMed Publisher
In one paragraph

Trial report in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Viktoria MargaryanDepartment of Oral and Maxillofacial Surgery, Yerevan State Medical University, Yerevan, Armenia.
Eduard AghasyanVivaldi Dental Clinic, Yerevan, Armenia.
Lazar YessayanDepartment of Therapeutic Stomatology, Yerevan State Medical University, Yerevan, Armenia.
Hakob KhachatryanDepartment of Oral and Maxillofacial Surgery, Yerevan State Medical University, Yerevan, Armenia.
Curd BollenCollege of Medicine & Dentistry, University of Ulster, Birmingham, UK.
Gagik HakobyanDepartment of Oral and Maxillofacial Surgery, Yerevan State Medical University, Yerevan, Armenia. hakobyan_gv@rambler.ru.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of the study is to compare the clinical efficacy of the application of "Armenicum" paste as an adjunct to SRP for the non-surgical treatment of patients with periodontitis.

methodsThe current RCT prospective study was conducted on 157 patients with chronic periodontitis. The patients were blind randomly assigned into two groups: Group A (SRP + Armenicum" paste) 81 patients (42 males and 39 females, 37 to 68 years) and Group B (SRP) 76 patients (39 males and 37 females, 37 to 68 years). Periodontal indices BOP, PPD, and DPI within each treatment group were measured before periodontal therapy, 3 and 6 months after the treatment. Group A underwent a periodontal treatment which included: supragingival and subgingival scaling, and additional use of local "Armenicum" paste. The Group B group only received supragingival and subgingival scaling.

resultsIn our study, the mean BOP, DPI, and PPD showed a statistically significant difference from baseline to 3 months and 6 months (p ≤ 0.05) in both Group A and Group B. But, mean BOP and mean PPD reduction gain was found to be greater in Group-A than Group B at 3 months and 6 months. No statistical differences in clinical indices were recorded depending on gender and age.

conclusionThese results indicate that topical "Armenicum" paste provides an effective adjunctive treatment of chronic periodontitis. CLINICAL RELEVANCE: The results of the current study showed that the adjunctive use of "Armenicum" reduced signs of inflammation compared to standard SRP treatment alone. Periodontal therapy using Armenicum paste application can be considered as a promising method in the treatment of periodontitis.

Indexed as

Chronic PeriodontitisDental ScalingAdultAgedCombined Modality TherapyFemaleHumansMaleMiddle AgedPeriodontal IndexProspective StudiesTreatment OutcomeAdjunctive therapyAntibacterial“Armenicum” pastePeriodontal treatmentPeriodontitisScalingSupragingival and subgingival

Identifiers

PMID39849187

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.