Evidence map›Paper›PMID 39849161›Full record

ArticleAnnals of hematology2025

Total marrow irradiation as part of autologous stem cell transplantation for patients with multiple myeloma.

Qing-Xiu Zhong, Fan-Yi Meng, Hong-Yu Chen, Xin Li, Xiao-Guo Wang, Shun-Hua Huang, Ming-Yan Wu, Jian-Hua Yu, Ying Xue, Yi-Hong Wu and 3 more

Abstract read
In one paragraph

Article in Annals of hematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Qing-Xiu ZhongDepartment of Hematology, Kanghua Hospital, Dongguan, Guangdong, P.R. China.
Fan-Yi MengDepartment of Hematology, Kanghua Hospital, Dongguan, Guangdong, P.R. China. mengfu@medmail.com.cn.
Hong-Yu ChenDepartment of Hematology, Kanghua Hospital, Dongguan, Guangdong, P.R. China.
Xin LiDepartment of Oncology, Kanghua Hospital, Dongguan, Guangdong, P.R. China.
Xiao-Guo WangDepartment of Hematology, Kanghua Hospital, Dongguan, Guangdong, P.R. China.
Shun-Hua HuangDepartment of Hematology, Kanghua Hospital, Dongguan, Guangdong, P.R. China.
Ming-Yan WuDepartment of Hematology, Kanghua Hospital, Dongguan, Guangdong, P.R. China.
Jian-Hua YuDepartment of Hematology, Kanghua Hospital, Dongguan, Guangdong, P.R. China.
Ying XueDepartment of Oncology, Kanghua Hospital, Dongguan, Guangdong, P.R. China.
Yi-Hong WuDepartment of Hematology, Dongguan Hospital of Traditional Chinese Medicine, Dongguan, Guangdong, P.R. China.
Da-Na YaoDepartment of Hematology, Kanghua Hospital, Dongguan, Guangdong, P.R. China.
Jia-Xin LongDepartment of Hematology, Kanghua Hospital, Dongguan, Guangdong, P.R. China.
Xiao-Hong HeDepartment of Hematology, Kanghua Hospital, Dongguan, Guangdong, P.R. China.

Funding

Dongguan social science and technology development project 202050715059413
6 · The paper itself

Abstract

The efficacy and safety of total marrow irradiation (TMI) plus a reduced dose of melphalan as autologous stem cell transplantation (ASCT) preconditioning for multiple myeloma (MM) patients were evaluated. The 11 patients with MM had a median age of 57 (range: 46-75) years; six of them were at standard risk and five of them were at high risk based on the Mayo Stratification of Myeloma and Risk-adapted Therapy (mSMART) standard risk factors. Before ASCT, three patients achieved stringent complete response (sCR), two patients achieved complete remission (CR), and the rest of the patients had either partial response (PR) or progressive disease. Most of the 11 patients were pretreated with melphalan 120-140 mg/m

Indexed as

Bone MarrowHematopoietic Stem Cell TransplantationMultiple MyelomaTransplantation ConditioningWhole-Body IrradiationAgedFemaleHumansMaleMelphalanMiddle AgedTransplantation, AutologousMelphalanAutologous stem cell transplantationMelphalanMultiple myelomaTotal marrow irradiation

Identifiers

PMID39849161
PMCPMC11868127

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.