ArticleScientific reports2025
Trends, global comparisons, and projections of early onset colorectal cancer burden in China based on GBD study 2021.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global, regional, national burden of colorectal cancer from 1990 to 2021, with projections of incidence to 2050: a systematic analysis of the global burden of disease study 2021.Frontiers in oncology · 2025Pooled it
- Global and China burden of maternal sepsis and infections: a systematic global burden of disease 2021 analysis with projections to 2036.The Journal of the Egyptian Public Health Association · 2026Article
- The prognostic value of the albumin/neutrophil-to-lymphocyte ratio in colorectal cancer patients: a retrospective cohort study.Frontiers in oncology · 2026Article
- Early Detection and Age-Comparative Analysis of Colorectal Cancer Screening: Insights from the Turkish Population.Current oncology (Toronto, Ont.) · 2025Article
- Neonatal encephalopathy due to birth asphyxia and trauma: global trends and disparities.Frontiers in public health · 2025Article
- The association between neutrophil percentage to albumin ratio and progression-free survival and overall survival in colorectal cancer patients: a retrospective cohort study.Frontiers in nutrition · 2025Article
- Global, regional, and national burden of early-onset colorectal cancer attributable to high BMI (1990-2021).Frontiers in medicine · 2025Article
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Authors and funding
5 authors.
Funding
Abstract
This study aimed to analyze the trends of early-onset colorectal cancer (EOCRC) among individuals aged 15 to 49 in China from 1990 to 2021 and compare them with global patterns using data from the Global Burden of Disease (GBD) study. The analysis focused on age-standardized incidence rates (ASIR), prevalence rates (ASPR), mortality rates (ASMR), and disability-adjusted life years (DALYs). Joinpoint regression was used to determine the average annual percentage change (AAPC), and the ARIMA model was employed to forecast trends from 2022 to 2050. Results showed a significant increase in ASIR and ASPR in China, with a more rapid rise compared to global trends. ASMR and DALYs showed a decline, indicating improved survival rates. However, the increasing DALYs in China suggest a growing health impact. The ARIMA projections indicate a continued increase in EOCRC burden in China, highlighting the need for enhanced prevention and early detection strategies. This study underscores the necessity for intensified public health interventions to address the rising incidence of EOCRC in China.
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