ArticleScientific reports2025
Assessing blood flow in uterine fibroids using intravoxel incoherent motion imaging compared with dynamic contrast-enhanced MRI.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Understanding different aspects of blood supply of uterine fibroids: an overview of ultrasound and magnetic resonance imaging techniques.Insights into imaging · 2025Article
- An explanation for the triphasic dependency of apparent diffusion coefficient (ADC) on T2 relaxation time: the multiple T2 compartments model.Quantitative imaging in medicine and surgery · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To assess the utility of IVIM parameters in evaluating uterine fibroid blood flow compared to dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) derived blood flow. Sixteen premenopausal women with uterine fibroids were enrolled in this prospective study. Pelvic MRI scans were obtained for each subject, both with and without continuous intravenous infusion of oxytocin, known to decrease significantly uterine fibroid blood flow, to assess the changes in blood flow of uterine fibroids. IVIM and DCE analyses were conducted using separate dedicated software. The bi-exponential IVIM model was used to estimate perfusion fraction (f), pseudo-diffusion coefficient (D*), and diffusion coefficient (D). DCE blood flow values were derived via T1 perfusion deconvolution arithmetic, utilizing a first pass of an AIF curve. The correlation between the parameters were analyzed by Spearman's rank correlation analysis due to small sample size. Means of the parameters were compared with a nonparametric Wilcoxon sign rank method for each pair. Statistically significant positive correlations were found between perfusion fraction values and DCE blood flow values with oxytocin (Spearson's ρ = 0.78, p = 0.0004), and between fD* values and DCE blood flow values with oxytocin (Spearson's ρ = 0.64, p = 0.0071). Significant differences in blood flow were detected across most IVIM parameters: f, D*, and fD* (p < 0.001, p = 0.0027, and p = 0.0002, respectively) when comparing the values without oxytocin and with oxytocin. IVIM imaging shows promise for assessing blood flow in uterine fibroids.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.