Evidence map›Paper›PMID 39848838›Full record

ReviewTrends in neurosciences2025

Making sense of vertebrate senses from a neural crest and cranial placode evo-devo perspective.

Brittany M Edens, Marianne E Bronner

Abstract readReview
In one paragraph

Review in Trends in neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. The molecular evolution of vertebrate organs.Nature ecology & evolution · 2026
    Review
  3. Article
  4. Re-make, re-model: evolution and development of vertebrate cranial lateral lines.Biological reviews of the Cambridge Philosophical Society · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Brittany M EdensDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Marianne E BronnerDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address: mbronner@caltech.edu.

Funding

Progressive acquisition of novel neural crest derivatives along the neural axis during vertebrate evolutionR35NS111564 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI Marianne Bronner · 2019 to 2026
$5.0M
Analysis of transcriptional priming of progenitors in the vertebrate neural plate borderF32HD106627 · NICHD · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI EDENS, BRITTANY MEGAN · 2021 to 2024
$209k
NICHD NIH HHS F32 HD106627NINDS NIH HHS R35 NS111564
6 · The paper itself

Abstract

The evolution of vertebrates from protochordate ancestors marked the beginning of the gradual transition to predatory lifestyles. Enabled by the acquisition of multipotent neural crest and cranial placode cell populations, vertebrates developed an elaborate peripheral nervous system, equipped with paired sense organs, which aided in adaptive behaviors and ultimately, successful colonization of diverse environmental niches. Underpinning the enduring success of vertebrates is the highly adaptable nature of the peripheral nervous system, which is enabled by the exceptional malleability of the neural crest and placode developmental programs. Here, we explore the embryonic origins of the vertebrate senses from the neural crest and cranial placodes and discuss the evolutionary trajectory of the senses in the context of adaptation to novel environments.

Indexed as

Biological EvolutionNeural CrestSkullVertebratesAnimalsHumansgene regulatory networkneural plate borderNew Head Hypothesisperipheral nervous systemsense organswater-to-land transition

Identifiers

PMID39848838
PMCPMC11903184

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.