Evidence map›Paper›PMID 39848704›Full record

ArticleBJGP open2025

Patients' reasons for declining a primary care trial online therapy: a mixed-methods study.

Fiona Fox, Debbie Tallon, Roz Shafran, Paul Lanham, Christopher Williams, Berry Jude, Nicola Wiles, David Kessler, Katrina Turner

Abstract read
In one paragraph

Article in BJGP open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fiona FoxNIHR ARC West, Bristol, UK f.fox@bristol.ac.uk.ORCID https://orcid.org/0000-0001-7313-8105
Debbie TallonCentre for Academic Mental Health, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.ORCID https://orcid.org/0000-0001-9195-5010
Roz ShafranGreat Ormond Street Institute of Child Health, University College London, London, UK.ORCID https://orcid.org/0000-0003-2729-4961
Paul LanhamPublic and Patient Involvement Representative, London, UK.
Christopher WilliamsInstitute of Health and Wellbeing, University of Glasgow, Glasgow, UK.ORCID https://orcid.org/0000-0001-5387-2863
Berry JudeUCL Division of Psychiatry, Maple House, London, UK.ORCID https://orcid.org/0009-0001-8612-0630
Nicola WilesCentre for Academic Mental Health, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.ORCID https://orcid.org/0000-0002-5250-3553
David KesslerCentre for Academic Mental Health, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.ORCID https://orcid.org/0000-0001-5333-132X
Katrina TurnerPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.ORCID https://orcid.org/0000-0002-6375-2918

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntegrating therapist-led sessions and cognitive behavioural therapy (CBT) materials within one online platform may be effective for people with depression. A trial evaluating this mode of delivering CBT is being conducted. To maximise future trial recruitment and understand patients' views of health interventions, it is important to explore reasons for declining to participate.

aimTo explore patients' reasons for declining to participate in a trial of integrated online CBT for depression. DESIGN &

settingA mixed-methods study collecting data from patients via questionnaires and telephone interviews at three UK trial sites.

methodIndividuals completed a short questionnaire about their reasons for not taking part in the trial. Telephone interviews further explored these reasons with a subgroup. Quantitative data were summarised using descriptive statistics. Qualitative interviews were analysed thematically.

resultsOf 1799 patients who responded to an invitation to participate in the trial, 40.3% declined contact. The most common reasons were not wanting: to take part in research (

conclusionReasons given by primary care patients for not taking part in a trial of integrated online CBT suggest that, at the point of recruitment, it is important to discuss the patient's perceptions of their eligibility and whether they would accept the intervention being evaluated.

Indexed as

cognitive behavioural therapydepressionmental healthprimary health carerandomised controlled trials

Identifiers

PMID39848704
PMCPMC12728872

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.