Evidence map›Paper›PMID 39848437›Full record

ArticleJournal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus2025

Adaptive functioning and relationship to visual behavior in children with cerebral/cortical visual impairment.

Randy Nguyen, Sharon H O'Neil, Mark S Borchert, Melinda Y Chang

Abstract read
In one paragraph

Article in Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Randy NguyenKeck School of Medicine of USC, Los Angeles, California.
Sharon H O'NeilDepartment of Pediatrics, Division of Neurology, Children's Hospital Los Angeles, Los Angeles, California.
Mark S BorchertKeck School of Medicine of USC, Los Angeles, California; Division of Ophthalmology, Children's Hospital Los Angeles, Los Angeles, California.
Melinda Y ChangKeck School of Medicine of USC, Los Angeles, California; Division of Ophthalmology, Children's Hospital Los Angeles, Los Angeles, California. Electronic address: melinda.y.wu@gmail.com.

Funding

Validating a machine learning model of eye tracking in children with cortical visual impairment (CVI)K23EY033790 · NEI · CHILDREN'S HOSPITAL OF LOS ANGELES · PI Melinda Chang · 2022 to 2026
$1.2M
NEI NIH HHS K23 EY033790
6 · The paper itself

Abstract

backgroundCerebral/cortical visual impairment (CVI) is a leading cause of pediatric visual impairment in developed countries and is associated with neurologic conditions that may impair adaptive functioning or skills required to perform everyday tasks (eg, communication, socialization, and daily living skills). Adaptive behavior in children with CVI has not been systematically studied, and the relationship between visual function and adaptive function in CVI is unknown.

methodsWe prospectively recruited 49 children with CVI (mean age, 4 ± 3 years). Adaptive behavior was evaluated using the Vineland Adaptive Behavior Scale, 3rd edition (VABS-III). Visual acuity was assessed by a pediatric neuro-ophthalmologist using the six-level Visual Behavior Scale (VBS). The relationship between VBS and VABS-III scores was assessed using a Spearman correlation coefficient and a multiple regression model to correct for age, sex, and neurologic and ophthalmologic comorbidities.

resultsIn our cohort, mean adaptive behavior scores in children with CVI were below the 1st percentile on all VABS-III domains and subdomains. Visual acuity, as assessed by VBS, was significantly associated with VABS-III total adaptive behavior composite score (P = 0.04), socialization (P = 0.03) domain, and interpersonal (P = 0.04), play and leisure (P = 0.04), and personal (P = 0.01) subdomains.

conclusionsChildren with CVI have significantly reduced adaptive functioning. Visual behavior is correlated with socialization and some daily living skills. Future longitudinal studies should evaluate whether adaptive functioning increases as visual acuity improves in children with CVI, which may have prognostic implications.

Indexed as

Adaptation, PsychologicalBlindness, CorticalVision DisordersVisual AcuityActivities of Daily LivingChildChild, PreschoolFemaleHumansMaleProspective Studies

Identifiers

PMID39848437
PMCPMC11885022

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.