Evidence map›Paper›PMID 39848329›Full record

ArticleJournal of vascular and interventional radiology : JVIR2025

Transmission-Based Monitoring of Dual-Applicator Microwave Ablation Discriminates Discontiguous from Contiguous Ablation Zones in an In Vivo Porcine Liver Model.

Nooshin Zeinali, Austin Pfannenstiel, Clay Hallman, Haileigh Avellar, Brandon L Plattner, David S Hodgson, Alana Moberly, Jude Conley, Anna Bottiglieri, Jan Sebek and 2 more

Abstract read
In one paragraph

Article in Journal of vascular and interventional radiology : JVIR, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nooshin ZeinaliDepartment of Electrical and Computer Engineering, Kansas State University, Manhattan, Kansas.
Austin PfannenstielDepartment of Electrical and Computer Engineering, Kansas State University, Manhattan, Kansas; Precision Microwave, Inc., Manhattan, Kansas.
Clay HallmanDepartment of Clinical Sciences, Kansas State University, Manhattan, Kansas.
Haileigh AvellarDepartment of Clinical Sciences, Kansas State University, Manhattan, Kansas.
Brandon L PlattnerDepartment of Diagnostic Medicine/Pathobiology, Kansas State University, Manhattan, Kansas.
David S HodgsonDepartment of Clinical Sciences, Kansas State University, Manhattan, Kansas.
Alana MoberlyDepartment of Clinical Sciences, Kansas State University, Manhattan, Kansas.
Jude ConleyPrecision Microwave, Inc., Manhattan, Kansas.
Anna BottiglieriDepartment of Electrical and Computer Engineering, Kansas State University, Manhattan, Kansas; Department of Biomedical Engineering, The George Washington University, Washington, DC.
Jan SebekDepartment of Electrical and Computer Engineering, Kansas State University, Manhattan, Kansas.
Francois H CornelisMemorial Sloan Kettering Cancer Center, New York, New York; Weill Cornell Medical College, Department of Radiology, New York, New York.
Punit PrakashDepartment of Electrical and Computer Engineering, Kansas State University, Manhattan, Kansas; Department of Biomedical Engineering, The George Washington University, Washington, DC. Electronic address: punit.prakash@gwu.edu.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
MWA verification system for improved confidence in treatment outcomesR43CA265482 · NCI · PRECISION MICROWAVE, INC. · PI PFANNENSTIEL, AUSTIN · 2022 to 2022
$400k
NCI NIH HHS P30 CA008748NCI NIH HHS R43 CA265482
6 · The paper itself

Abstract

purposeTo determine the technical feasibility of discriminating discontiguous from contiguous ablation zones between a pair of microwave ablation (MWA) applicators using broadband microwave transmission signal measurements in an in vivo porcine liver model. MATERIALS AND

methodsDual applicator 2.45 GHz MWA was performed using 1 directional and 1 omnidirectional applicator, spaced 3 cm apart, under imaging guidance. The study involved 15 hepatic MWAs across 4 swine, with ablation durations of 200 seconds (n = 8) for discontiguous ablation and 600 seconds (n = 7) for contiguous ablation, each at 60 W; these ablation durations and applied power combinations were selected with the intent of creating discontiguous (200 s) and contiguous (600 s) ablation zones. A custom software periodically measured transmission signals between the applicators at 46-second intervals. Contrast-enhanced computed tomography (CT), gross pathology, and histopathologic analyses were used to assess the processed transmission signal (PTS).

resultsStatistical analyses revealed significant differences between contiguous and discontiguous ablation zones on contrast-enhanced CT imaging (volume, 16.9 cm

conclusionsThis study demonstrated that PTS between dual MWA applicators can distinguish between contiguous and discontiguous ablation zones.

Indexed as

Ablation TechniquesLiverMicrowavesAnimalsEquipment DesignFeasibility StudiesModels, AnimalRadiography, InterventionalSus scrofaSwineTime FactorsTomography, X-Ray Computed

Identifiers

PMID39848329
PMCPMC12033080

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.