Trial reportJAMA ophthalmology2025
Femtosecond Laser Arcuate Keratotomy vs Toric Intraocular Lens Implantation in Cataract Surgery: A Randomized Clinical Trial.
Trial report in JAMA ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Aligning the Axis of Toric Intraocular Lens with the Corneal Steep Meridian by Setting SIA at 0 Diopter: A Prospective Randomized Controlled Trial.Clinical ophthalmology (Auckland, N.Z.) · 2026Trial
- Advances in cataract surgery: is a new era on the horizon?Current opinion in ophthalmology · 2026Review
- Implantable collamer lens combined with femtosecond laser-assisted arcuate keratotomy and toric implantable collamer lens for high myopia with moderate-to-low astigmatism corrections: a comparative study.BMC ophthalmology · 2026Article
- A capsular tension ring improves postoperative visual quality in cataract patients by reducing intraocular lens decentration and tilt.American journal of translational research · 2026Article
- Effectiveness of Topical Anesthesia in Patients Undergoing Phacoemulsification Cataract Surgery versus Femtosecond Laser-Assisted Cataract Surgery.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Comparative effectiveness of toric IOLs and LRIs for correction of moderate regular astigmatism during phacoemulsification.Scientific reports · 2025Article
- Cataract: Surgery first - is there still room for basic research?Advances in ophthalmology practice and researchReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Importance: After cataract surgery, postoperative residual astigmatism can influence a patient's visual quality and satisfaction. Finding ways to minimize this astigmatism is important. Objective: To compare the clinical outcomes of femtosecond laser arcuate keratotomy (FSAK) and toric intraocular lens (TIOL) implantation for astigmatism correction in patients undergoing femtosecond laser-assisted cataract surgery. Design, Setting, and Participants: This randomized clinical trial was conducted between October 2021 and September 2023 at the Eye Center of the Second Affiliated Hospital, School of Medicine, Zhejiang University, China. Patients with mild to moderate regular corneal astigmatism ranging from 0.75 diopters (D) to 3.00 D were recruited. Interventions: Patients were randomly assigned in a 1:1 ratio to receive FSAK or TIOL implantation. Main Outcomes and Measures: The primary outcome was the subjective manifest refraction assessed at 3 months postoperatively. Results: A total of 196 patients (mean [SD] age, 68.4 [13.7] years; 124 female [63%]) were randomized to the FSAK group (98 [50%]) or TIOL group (98 [50%]), and 92 patients (94%) and 95 patients (97%), respectively, finished the 3-month follow-up. At 3 months postoperatively, there was no difference in the refractive astigmatism between the 2 groups (mean [SD], 0.64 [0.64] D vs 0.54 [0.55] D; difference, 0.11 D; 95% CI, -0.06 to 0.27 D; P = .21). The mean (SD) uncorrected distance visual acuity was 0.15 (0.20) logMAR (Snellen equivalent, 20/28) for the FSAK group and 0.14 (0.19) logMAR (Snellen equivalent, 20/28) for the TIOL group (difference, 0.01 D; 95% CI, -0.04 to 0.06 D; P = .71). Subgroup analyses showed that TIOL implantation achieved lower residual astigmatism compared with FSAK when treating astigmatism exceeding 1.5 D or against-the-rule astigmatism. Conclusions and Relevance: Results of this randomized clinical trial demonstrate that in study participants with mild to moderate astigmatism undergoing femtosecond laser-assisted cataract surgery, FSAK was not superior to TIOL implantation for astigmatism correction. However, for astigmatism exceeding 1.5 D or against-the-rule astigmatism, TIOL implantation demonstrated greater efficacy over FSAK. Future trials are needed to determine if there is greater efficacy of TIOL implantation over FSAK as suggested by subgroup analyses. Trial Registration: ChiCTR.org.cn Identifier: ChiCTR2100051066.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.