Evidence map›Paper›PMID 39847261›Full record

SynthesisGeneral thoracic and cardiovascular surgery2025

Off-pump versus on-pump coronary artery bypass grafting in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis.

Anelise Poluboiarinov Cappellaro, Luiz F Costa de Almeida, Manoela Lenzi Pinto, Marcelo Albuquerque Barbosa Martins, Augusto Graziani E Sousa, Júlia Gonçalves Gadelha, Ana Carolina Putini Vieira, Luís Fernando Rosati Rocha, Myat Soe Thet

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in General thoracic and cardiovascular surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anelise Poluboiarinov CappellaroCentro Universitário Maurício de Nassau de Barreiras, Barreiras, Brazil.
Luiz F Costa de AlmeidaDepartment of Surgery, Federal Fluminense University, Niterói, Brazil.
Manoela Lenzi PintoUniversidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.
Marcelo Albuquerque Barbosa MartinsUniversidade Federal de Ouro Preto, Ouro Preto, Brazil.
Augusto Graziani E SousaCentro Universitário de Anápolis, Anápolis, Brazil.
Júlia Gonçalves GadelhaAfya Faculdade de Ciências Médicas da Paraíba, João Pessoa, Brazil.
Ana Carolina Putini VieiraUniversidade Santo Amaro, São Paulo, Brazil.
Luís Fernando Rosati RochaDepartment of Surgery, Federal Fluminense University, Niterói, Brazil.
Myat Soe ThetDepartment of Surgery & Cancer, Imperial College London, South Kensington, United Kingdom. m.thet21@imperial.ac.uk.ORCID http://orcid.org/0000-0002-2741-0339

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOff-pump coronary artery bypass graft surgery (OPCAB) has been suggested as superior to on-pump coronary artery bypass graft surgery (ONCAB) in certain high-risk subgroups, but its benefit in patients with chronic obstructive pulmonary disease (COPD) remains controversial. This meta-analysis aimed to evaluate OPCAB versus ONCAB outcomes in COPD patients.

methodsWe followed PRISMA guidelines and searched PubMed, Embase, and the Cochrane Library in August 2024 for studies comparing OPCAB and ONCAB in COPD patients. Statistical analysis was conducted using Review Manager 5.4.1 and Rstudio with a fixed or random effects model.

resultsSix studies with a total of 1,687 patients were included, of which 1,062 (62.95%) underwent OPCAB. The mean patient age was 63.6 years. OPCAB did not significantly affect all-cause mortality compared to ONCAB (OR 1.14; 95% CI 0.65-1.99). There were no significant differences in reintubation (OR 0.81; 95% CI 0.53-1.23), prolonged ventilation (OR 0.54; 95% CI 0.24-1.22), post-operative atrial fibrillation (OR 0.90; 95% CI 0.70-1.15), or ARDS (OR 0.43; 95% CI 0.14-1.33). However, ventilation time was significantly shorter in the OPCAB group (MD - 5.30 h; 95% CI - 7.22 to - 3.38).

conclusionOPCAB is associated with reduced ventilation time in COPD patients though it shows no significant difference in all-cause mortality or other post-operative complications compared to ONCAB.

Indexed as

Coronary Artery BypassCoronary Artery Bypass, Off-PumpCoronary Artery DiseasePulmonary Disease, Chronic ObstructiveAgedFemaleHumansMaleMiddle AgedPostoperative ComplicationsRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeChronic obstructive pulmonary diseaseCoronary artery bypass graftingMeta-analysisOff-pumpOn-pump

Identifiers

PMID39847261
PMCPMC11914329

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.