Evidence map›Paper›PMID 39847217›Full record

ArticleDoklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections2025

In Vivo UV-Induced Fluorescence Spectroscopy of Skin in Parkinson's Disease.

V V Salmin, V B Loschenov, A B Ochirova, N P Bainaev-Mangilev, M N Andreev, E Yu Fedotova, A B Salmina, S N Illarioshkin

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Article in Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

V V SalminMoscow Institute of Physics and Technology, Dolgoprudny, Russia. vsalmin@gmail.com.
V B LoschenovNational Research Nuclear University, Moscow Engineering Physics Institute, Moscow, Russia.
A B OchirovaNational Research Nuclear University, Moscow Engineering Physics Institute, Moscow, Russia.
N P Bainaev-MangilevNational Research Nuclear University, Moscow Engineering Physics Institute, Moscow, Russia.
M N AndreevResearch Center of Neurology, Moscow, Russia.
E Yu FedotovaResearch Center of Neurology, Moscow, Russia.
A B SalminaResearch Center of Neurology, Moscow, Russia.
S N IllarioshkinResearch Center of Neurology, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Characteristic patterns of UV-induced skin autofluorescence were determined for patients with Parkinson's disease (PD) and associated with dysmetabolic alterations, such as nonenzymatic protein glycation, an increase in extracellular matrix stiffness, impaired metabolism of tissue fluorophores, mitochondrial dysfunction, and accumulation of aberrant proteins. Key differences in skin autofluorescence spectra were for the first time observed in PD, making it possible to discriminate between PD patients and healthy persons or individuals without signs of chronic neurodegeneration. Namely, skin fluorescence related to the reflected signal upon excitation with UV light at 375 nm was lower in PD patients.

Indexed as

Parkinson DiseaseSkinUltraviolet RaysAgedFemaleHumansMaleMiddle AgedSpectrometry, Fluorescenceadvanced glycation end-productsfluorescence spectroscopyParkinson’s diseaseskinα-synuclein

Identifiers

PMID39847217

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.