Evidence map›Paper›PMID 39846767›Full record

ArticleJournal of veterinary internal medicine

Echocardiographic evaluation of the size of the main pulmonary artery and right pulmonary artery in dogs with pulmonary hypertension.

Giovanni Grosso, Rosalba Tognetti, Oriol Domenech, Andrea Della Pina, Federica Marchesotti, Valentina Patata, Tommaso Vezzosi

Abstract readMulticenter StudyObservational Study, Veterinary
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giovanni GrossoDepartment of Veterinary Sciences, University of Pisa, Pisa, Italy.ORCID https://orcid.org/0000-0002-3737-2444
Rosalba TognettiDepartment of Veterinary Sciences, University of Pisa, Pisa, Italy.ORCID https://orcid.org/0000-0001-8449-9176
Oriol DomenechDepartment of Cardiology, Anicura Istituto Veterinario Novara, Novara, Italy.
Andrea Della PinaDepartment of Veterinary Sciences, University of Pisa, Pisa, Italy.
Federica MarchesottiDepartment of Cardiology, Anicura Istituto Veterinario Novara, Novara, Italy.
Valentina PatataDepartment of Cardiology, Anicura Istituto Veterinario Novara, Novara, Italy.ORCID https://orcid.org/0000-0002-5123-5323
Tommaso VezzosiDepartment of Veterinary Sciences, University of Pisa, Pisa, Italy.ORCID https://orcid.org/0000-0001-8301-6582

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEvaluating the size of the pulmonary artery (PA) is key for the echocardiographic assessment of pulmonary hypertension (PH) in dogs. HYPOTHESIS/

objectivesTo compare the diagnostic accuracy of the main PA (MPA) and right PA (RPA) sizes for the echocardiographic detection of PH in dogs, and to evaluate differences between precapillary and postcapillary PH dogs. ANIMALS: Four hundred four dogs; 136 controls and 268 with PH.

methodsProspective, multicenter, observational study. The MPA, maximum and minimum RPA diameter were normalized to body weight (MPA_N, RPAmax_N, and RPAmin_N). The MPA was also indexed to the ascending aorta (MPA/AO), while the RPA size was indexed to the aortic annulus (RPAmax/Aod and RPAmin/Aod). The right pulmonary artery distensibility index (RPADi) was also calculated. The diagnostic accuracy of PA parameters for PH was assessed through the receiver operating characteristic curve analysis and area under the curve (AUC). Measurement variability was assessed trough the coefficient of variation (CV).

resultsThe RPADi, RPAmin_N, and RPAmin/Aod showed similar diagnostic accuracy for the detection of PH (AUC = 0.975, AUC = 0.971, and AUC = 0.953, respectively), higher than MPA/AO (AUC = 0.926), MPA_N (AUC = 0.880), RPAmax_N (AUC = 0.814), and RPAmax/Aod (AUC = 0.803; P < .05). Aside from RPAmax variables, no differences were found between precapillary and postcapillary PH. RPA size parameters showed lower CVs in comparison to MPA/AO and RPADi. CONCLUSIONS AND CLINICAL IMPORTANCE: Although MPA/AO showed an excellent sensitivity and specificity for the detection of PH, the RPAmin exhibited a higher diagnostic accuracy and less measurement variability, thus could represent a new useful parameter for the detection of PH in dogs.

Indexed as

Dog DiseasesEchocardiographyHypertension, PulmonaryPulmonary ArteryAnimalsDogsFemaleMaleProspective Studiescaninecardiologypostcapillaryprecapillarytricuspid regurgitation

Identifiers

PMID39846767
PMCPMC11755767

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.