Evidence map›Paper›PMID 39846750›Full record

ArticleApplied and environmental microbiology2025

Laboratory evolution in

Marco N Allemann, Ryo Kato, Dana L Carper, Leah H Hochanadel, William G Alexander, Richard J Giannone, Naofumi Kamimura, Eiji Masai, Joshua K Michener

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marco N AllemannBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA.ORCID 0000-0002-9290-7296
Ryo KatoDepartment of Materials Science and Bioengineering, Nagaoka University of Technology, Nagaoka, Niigata, Japan.ORCID 0000-0003-1478-6625
Dana L CarperBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA.ORCID 0000-0002-4758-8054
Leah H HochanadelBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA.
William G AlexanderBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA.ORCID 0000-0003-4212-6392
Richard J GiannoneBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA.ORCID 0000-0001-8551-0138
Naofumi KamimuraDepartment of Materials Science and Bioengineering, Nagaoka University of Technology, Nagaoka, Niigata, Japan.ORCID 0000-0002-8792-1675
Eiji MasaiDepartment of Materials Science and Bioengineering, Nagaoka University of Technology, Nagaoka, Niigata, Japan.ORCID 0000-0001-9194-7483
Joshua K MichenerBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA.ORCID 0000-0003-2302-8180

Funding

DOE | SC | Biological and Environmental Research (BER)MEXT | Japan Science and Technology Agency (JST) JPMJPF2104
6 · The paper itself

Abstract

Lignin contains a variety of interunit linkages, leading to a range of potential decomposition products that can be used as carbon and energy sources by microbes. β-O-4 linkages are the most common in native lignin, and associated catabolic pathways have been well characterized. However, the fate of the mono-aromatic intermediates that result from β-O-4 dimer cleavage has not been fully elucidated. Here, we used experimental evolution to identify mutant strains of

Indexed as

LigninSphingomonadaceaeBacterial ProteinsDirected Molecular EvolutionGuaifenesinBacterial Proteinsguaiacylglycerol-beta-guaiacyl etherGuaifenesinLigninGGEligninNovosphingobium aromaticivorans

Identifiers

PMID39846750
PMCPMC11837543

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.