Evidence map›Paper›PMID 39846747›Full record

ReviewJournal of bacteriology2025

Gut phages and their interactions with bacterial and mammalian hosts.

Marshall Godsil, Nathaniel L Ritz, Siddarth Venkatesh, Alexander J Meeske

Abstract readReview
In one paragraph

Review in Journal of bacteriology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Robust detection in faeces andVeterinary and animal science · 2026
    Article
  4. Gut virome dynamics: from commensal to critical player in health and disease.Nature reviews. Gastroenterology & hepatology · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marshall GodsilDepartment of Microbiology, University of Washington, Seattle, Washington, USA.ORCID 0009-0007-0800-8559
Nathaniel L RitzInstitute for Systems Biology, Seattle, Washington, USA.
Siddarth VenkateshInstitute for Systems Biology, Seattle, Washington, USA.
Alexander J MeeskeDepartment of Microbiology, University of Washington, Seattle, Washington, USA.ORCID 0000-0003-3878-531X

Funding

CRISPR-Cas13 immunity in Listeria seeligeriR35GM142460 · NIGMS · UNIVERSITY OF WASHINGTON · PI Alexander Jacob Meeske · 2021 to 2026
$2.7M
Viral Pathogenesis Training ProgramT32AI083203 · NIAID · UNIVERSITY OF WASHINGTON · PI BLOOM, JESSE D, LAGUNOFF, MICHAEL · 2009 to 2023
$2.7M
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) T32AI083203HHS | NIH | National Institute of General Medical Sciences (NIGMS) R35GM142460National Science Foundation (NSF) FAIN2235762NIAID NIH HHS T32 AI083203NIGMS NIH HHS R35 GM142460Rita Allen Foundation (RAF)William K. Bowes, Jr. Foundation
6 · The paper itself

Abstract

The mammalian gut microbiome is a dense and diverse community of microorganisms that reside in the distal gastrointestinal tract. In recent decades, the bacterial members of the gut microbiome have been the subject of intense research. Less well studied is the large community of bacteriophages that reside in the gut, which number in the billions of viral particles per gram of feces, and consist of considerable unknown viral "dark matter." This community of gut-residing bacteriophages, called the gut "phageome," plays a central role in the gut microbiome through predation and transformation of native gut bacteria, and through interactions with their mammalian hosts. In this review, we will summarize what is known about the composition and origins of the gut phageome, as well as its role in microbiome homeostasis and host health. Furthermore, we will outline the interactions of gut phages with their bacterial and mammalian hosts, and plot a course for the mechanistic study of these systems.

Indexed as

BacteriaBacteriophagesGastrointestinal MicrobiomeGastrointestinal TractHost Microbial InteractionsMammalsAnimalsHumansmicrobiomephages

Identifiers

PMID39846747
PMCPMC11844821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.