Evidence map›Paper›PMID 39846430›Full record

ArticleAnimal models and experimental medicine2025

High-throughput markerless pose estimation and home-cage activity analysis of tree shrew using deep learning.

Yangzhen Wang, Feng Su, Rixu Cong, Mengna Liu, Kaichen Shan, Xiaying Li, Desheng Zhu, Yusheng Wei, Jiejie Dai, Chen Zhang and 1 more

Abstract read
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Article in Animal models and experimental medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Yangzhen WangDepartment of Automation, Tsinghua University, Beijing, China.
Feng SuCollege of Future Technology, Peking University, Beijing, China.
Rixu CongMinistry of Education, Key Laboratory of Cell Proliferation and Differentiation, College of Life Sciences, Peking University, Beijing, China.
Mengna LiuSchool of Basic Medical Sciences, Beijing Key Laboratory of Neural Regeneration and Repair, Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China.
Kaichen ShanDepartment of Automation, Tsinghua University, Beijing, China.
Xiaying LiLaboratory Animal Center, School of Life Sciences, Peking University, Beijing, China.
Desheng ZhuLaboratory Animal Center, School of Life Sciences, Peking University, Beijing, China.
Yusheng WeiLaboratory Animal Center, School of Life Sciences, Peking University, Beijing, China.
Jiejie DaiInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, China.
Chen ZhangSchool of Basic Medical Sciences, Beijing Key Laboratory of Neural Regeneration and Repair, Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China.
Yonglu TianSchool of Psychological and Cognitive Sciences, IDG/McGovern Institute for Brain Research, Peking University, Beijing, China.ORCID 0000-0002-1036-767X

Funding

China Postdoctoral Science Foundation 2020M670027China Postdoctoral Science Foundation 2023TQ0183Local Standards Research of BeiJing Laboratory Tree Shrew CHYX-2023-DGB001National Key Research and Development Program of China 2023YFF0724902
6 · The paper itself

Abstract

backgroundQuantifying the rich home-cage activities of tree shrews provides a reliable basis for understanding their daily routines and building disease models. However, due to the lack of effective behavioral methods, most efforts on tree shrew behavior are limited to simple measures, resulting in the loss of much behavioral information.

methodsTo address this issue, we present a deep learning (DL) approach to achieve markerless pose estimation and recognize multiple spontaneous behaviors of tree shrews, including drinking, eating, resting, and staying in the dark house, etc.

resultsThis high-throughput approach can monitor the home-cage activities of 16 tree shrews simultaneously over an extended period. Additionally, we demonstrated an innovative system with reliable apparatus, paradigms, and analysis methods for investigating food grasping behavior. The median duration for each bout of grasping was 0.20 s.

conclusionThis study provides an efficient tool for quantifying and understand tree shrews' natural behaviors.

Indexed as

Behavior, AnimalDeep LearningTupaiidaeAnimalsFemaleMaledeep learningfood graspinghome‐cage activitypose estimationtree shrew

Identifiers

PMID39846430
PMCPMC12107359

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.