Evidence map›Paper›PMID 39846398›Full record

ArticlePest management science2025

Long-term impact of exposure to Royal Guard, a pyriproxyfen-based bed net, on pyrethroid-resistant malaria vectors from Cameroon using DNA-based metabolic resistance markers.

Emilie S Ngongang-Yipmo, Magellan Tchouakui, Benjamin D Menze, Riccado F Tiomela, Derrick Fofie, Vanessa B Ngannang-Fezeu, Jean L Mugenzi, Flobert Njiokou, Charles S Wondji

Abstract read
In one paragraph

Article in Pest management science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Complex non-Research square · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Emilie S Ngongang-YipmoCentre for Research in Infectious Diseases (CRID), Yaoundé, Cameroon.ORCID https://orcid.org/0009-0002-0818-3377
Magellan TchouakuiCentre for Research in Infectious Diseases (CRID), Yaoundé, Cameroon.ORCID https://orcid.org/0000-0002-1683-8057
Benjamin D MenzeCentre for Research in Infectious Diseases (CRID), Yaoundé, Cameroon.
Riccado F TiomelaCentre for Research in Infectious Diseases (CRID), Yaoundé, Cameroon.
Derrick FofieCentre for Research in Infectious Diseases (CRID), Yaoundé, Cameroon.
Vanessa B Ngannang-FezeuCentre for Research in Infectious Diseases (CRID), Yaoundé, Cameroon.
Jean L MugenziCentre for Research in Infectious Diseases (CRID), Yaoundé, Cameroon.
Flobert NjiokouCentre for Research in Infectious Diseases (CRID), Yaoundé, Cameroon.
Charles S WondjiCentre for Research in Infectious Diseases (CRID), Yaoundé, Cameroon.

Funding

Bill and Melinda Gates FoundationWellcome Trust
6 · The paper itself

Abstract

backgroundEscalating pyrethroid resistance in malaria vectors highlights the urgency of implementing new control tools incorporating non-pyrethroid molecules. Here, using DNA-based metabolic resistance markers, we assessed the efficacy of the dual active ingredients net Royal Guard against pyrethroids-resistant malaria vectors in Cameroon, establishing its long-term impact on mosquitoes' life traits after exposure.

resultsCone assays revealed low efficacy of Royal Guard against field Anopheles populations. However, analysis of the survival curves revealed that unexposed mosquitoes lived longer (11.4 ± 0.4 days) than those exposed to Royal Guard (7.9 ± 0.2 days) (χ

conclusionThis study revealed that although pyrethroid-resistant mosquitoes have higher ability to survive and live longer after exposure to Royal Guard, this net significantly affects their lifespan, blood-feeding ability and interestingly reduces their fecundity/fertility. © 2025 The Author(s). Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Indexed as

AnophelesInsecticide ResistanceInsecticidesInsecticide-Treated BednetsMosquito ControlMosquito VectorsPyrethrinsPyridinesAnimalsCameroonFemaleMalariaInsecticidesPyrethrinsPyridinespyriproxyfenAnophelesDNA‐based markersfertilitylife‐traitslongevitymetabolic resistanceRoyal Guard

Identifiers

PMID39846398
PMCPMC11906912

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.