Evidence map›Paper›PMID 39846375›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Biomolecular Microneedle Initiates Fe

Wenjie You, Zichao Cai, Feng Xiao, Jiaxin Zhao, Guanyi Wang, Wang Wang, Zesheng Chen, Weikang Hu, Yun Chen, Zijian Wang

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Article
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  5. Article
  6. Article
  7. Review
  8. Recent Advances in Nanozymes Toward Diabetic Foot Ulcers.International journal of nanomedicine · 2026
    Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Biomolecular Microneedle Initiates FeAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wenjie YouDepartment of Urology, Institute of Urology, Cancer Precision Diagnosis and Treatment and Translational Medicine Hubei Engineering Research Center, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Zichao CaiOrthopedic Hospital, Postdoctoral Innovation Practice Base, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Feng XiaoOrthopedic Hospital, Postdoctoral Innovation Practice Base, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Jiaxin ZhaoOrthopedic Hospital, Postdoctoral Innovation Practice Base, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Guanyi WangDepartment of Urology, Institute of Urology, Cancer Precision Diagnosis and Treatment and Translational Medicine Hubei Engineering Research Center, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Wang WangDepartment of Urology, Institute of Urology, Cancer Precision Diagnosis and Treatment and Translational Medicine Hubei Engineering Research Center, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Zesheng ChenDepartment of Urology, Institute of Urology, Cancer Precision Diagnosis and Treatment and Translational Medicine Hubei Engineering Research Center, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Weikang HuSchool of Materials Science and Engineering, Stem Cells and Tissue Engineering Manufacture Center, Hubei University, Wuhan, 430062, China.
Yun ChenDepartment of Biomedical Engineering, Hubei Province Key Laboratory of Allergy and Immune Related Disease, TaiKang Medical School (School of Basic Medical Sciences), Wuhan University, Wuhan, 430071, China.
Zijian WangDepartment of Urology, Institute of Urology, Cancer Precision Diagnosis and Treatment and Translational Medicine Hubei Engineering Research Center, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.ORCID https://orcid.org/0000-0002-7285-0966

Funding

Chinese Medicine Science and Technology Program of Jiangxi Province 2023B1217Fellowship of China National Postdoctoral Program for Innovative Talents BX20220240Fundamental Research Funds for the Central Universities 2042023ky0080Hubei Provincial Natural Science Foundation of China 2023AFB880Postdoctoral Fellowship Program of CPSF GZC20241272
6 · The paper itself

Abstract

Reactive oxygen species (ROS) play a dual role in wound healing. They act as crucial signaling molecules and antimicrobial agents when present at moderate levels. However, excessive levels of ROS can hinder the healing process for individuals with diabetes. As a result, targeting ROS levels to maintain redox balance has become a promising strategy for improving wound recovery. Currently, no biomaterials have been reported to simultaneously up-regulate and down-regulate ROS to achieve broad-spectrum antibacterial and antioxidant properties. Inspired by the site-dependent effect of nanomaterials, a micron-sized ferroferric oxide (Fe

Indexed as

Diabetes Mellitus, ExperimentalFerroptosisWound HealingAnimalsAnti-Bacterial AgentsMaleNitritesRatsRats, Sprague-DawleyReactive Oxygen SpeciesTransition ElementsAnti-Bacterial AgentsMXeneNitritesReactive Oxygen SpeciesTransition ElementsferroptosismicroneedleMXenenanozymewound healing

Identifiers

PMID39846375
PMCPMC11923907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.