Evidence map›Paper›PMID 39846354›Full record

ArticleJournal of attention disorders2025

How Do Personality Dysfunction and Maladaptive Personality Traits Predict Time to Premature Discontinuation of Pharmacological Treatment of ADHD?

Peter Jacobsson, Tove Granqvist, Christopher J Hopwood, Robert F Krueger, Bo Söderpalm, Thomas Nilsson

Abstract read
In one paragraph

Article in Journal of attention disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Peter JacobssonUniversity of Gothenburg, Sweden.ORCID 0000-0002-5732-4386
Tove GranqvistTrana Psykologer, Varberg, Sweden.ORCID 0009-0007-0571-5813
Christopher J HopwoodUniversity of Zurich, Switzerland.
Robert F KruegerUniversity of Minnesota, Minneapolis, USA.
Bo SöderpalmUniversity of Gothenburg, Sweden.
Thomas NilssonUniversity of Gothenburg, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesNon-adherence to medication is common in the adult ADHD clinical group. The goal of this pre-registered study was to examine whether the DSM-5 Alternative Model of Personality Disorder (AMPD), generality personality dysfunction (LPFS-BF 2.0) or maladaptive personality traits (PID-5), can predict time to premature discontinuation of pharmacological treatment beyond other known factors.

methodsA sample of 284 adult patients with ADHD (60.6% female;

resultsOf the sample, 54 were found to have discontinued treatment prematurely without consulting their physician. Interestingly this group was prescribed considerably lower doses before discontinuation than adhering patients. General personality dysfunction and maladaptive antagonistic personality traits are implicated in varying degrees, with the specific maladaptive personality facets

conclusionsThe broader implication is that the emerging personality pathology models hold promise to predict non-adherence in the adult ADHD population.

Indexed as

Attention Deficit Disorder with HyperactivityMedication AdherencePersonalityPersonality DisordersAdultFemaleHumansMaleMiddle AgedYoung Adultadherenceadult ADHDalternative model of personality disorderpharmacological treatmentpremature discontinuation

Identifiers

PMID39846354
PMCPMC11800730

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.