Evidence map›Paper›PMID 39846333›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2025

Plasmonic Single-Molecule Affinity Detection at 10

Eleonora Macchia, Cinzia Di Franco, Cecilia Scandurra, Lucia Sarcina, Matteo Piscitelli, Michele Catacchio, Mariapia Caputo, Paolo Bollella, Gaetano Scamarcio, Luisa Torsi

Abstract read
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Plasmonic Single-Molecule Affinity Detection at 10Advanced materials (Deerfield Beach, Fla.) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eleonora MacchiaDipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Bari, 70125, Italy.ORCID https://orcid.org/0000-0002-1534-7336
Cinzia Di FrancoCNR IFN, Bari, 70125, Italy.ORCID https://orcid.org/0000-0003-3310-7878
Cecilia ScandurraDipartimento di Chimica, Università degli Studi di Bari Aldo Moro, Bari, 70125, Italy.ORCID https://orcid.org/0000-0002-6085-1910
Lucia SarcinaDipartimento di Chimica, Università degli Studi di Bari Aldo Moro, Bari, 70125, Italy.ORCID https://orcid.org/0000-0001-7797-029X
Matteo PiscitelliDipartimento Interateneo di Fisica, Università degli Studi di Bari Aldo Moro, Bari, 70125, Italy.ORCID https://orcid.org/0009-0003-8244-5002
Michele CatacchioDipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Bari, 70125, Italy.ORCID https://orcid.org/0009-0000-0640-9673
Mariapia CaputoDipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Bari, 70125, Italy.
Paolo BollellaDipartimento di Chimica, Università degli Studi di Bari Aldo Moro, Bari, 70125, Italy.ORCID https://orcid.org/0000-0001-9049-6406
Gaetano ScamarcioDipartimento Interateneo di Fisica, Università degli Studi di Bari Aldo Moro, Bari, 70125, Italy.ORCID https://orcid.org/0000-0003-0808-4336
Luisa TorsiDipartimento di Chimica, Università degli Studi di Bari Aldo Moro, Bari, 70125, Italy.ORCID https://orcid.org/0000-0002-0798-0780

Funding

Complementary National Plan PNC-I.1 "Research initiatives for innovative technologies and pathways in the health and welfare sector" 931 of 06/06/2022DARE - DigitAl lifelong pRevEntion initiative, code CUP: B53C22006420001DARE - DigitAl lifelong pRevEntion initiative, code PNC0000002HORIZON EUROPE European Research Council 101040383Instituto Nazionale di Fisica Nucleare PE0000023-NQSTIMinistero dell'agricoltura, della sovranità alimentare e delle foreste - MIPAAF D.M 419161 del 13/09/2022Ministero della Salute -code CUP: C43C22001630001Ministero della Salute -code PNC-E3-2022-23683266 PNC-HLS-DAPRIN project prot 2017RHX2E4The Centro di Innovazione Regionale Digital Assay, Regione PUGLIA Delibera Regionale n 702 del 08/11/2022 CUP B93C22000840001Xylella fastidiosa (REACH-XY) CUP B93C22001920001
6 · The paper itself

Abstract

DNA can be readily amplified through replication, enabling the detection of a single-target copy. A comparable performance for proteins in immunoassays has yet to be fully assessed. Surface-plasmon-resonance (SPR) serves as a probe capable of performing assays at concentrations typically around 10⁻⁹ molar. In this study, plasmonic single-molecule assays for both proteins and DNA are demonstrated, achieving limits-of-detections (LODs) as low as 10⁻

Indexed as

DNASingle Molecule ImagingSurface Plasmon ResonanceGoldHumansHydrogen-Ion ConcentrationLimit of DetectionMolarDNAGoldplasmonic sensorssingle‐molecule sensingsingle‐molecule with a large transistor (SiMoT)surface‐plasmon‐resonancesurface probing techniques

Identifiers

PMID39846333
PMCPMC11881672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.