Evidence map›Paper›PMID 39846278›Full record

ArticleJournal of the American Heart Association2025

Monocyte to High-Density Lipoprotein Ratio Is Associated With Carotid Plaque: A Retrospective Cohort Study.

Shuang Liu, Xinlei Miao, Manling Hu, Ziping Song, Xiaoling Xie, Yuting Sun, Meng Li, Guimin Tang, Song Leng

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shuang LiuHealth Management Center of the Second Affiliated Hospital of Dalian Medical University Dalian Liaoning China.ORCID 0009-0001-4284-7897
Xinlei MiaoHealth Management Center of the Second Affiliated Hospital of Dalian Medical University Dalian Liaoning China.
Manling HuDepartment of Gastroenterology of the Second Affiliated Hospital of Dalian Medical University Dalian Liaoning China.ORCID 0009-0000-9424-3385
Ziping SongDepartment of Gastroenterology of the Second Affiliated Hospital of Dalian Medical University Dalian Liaoning China.ORCID 0009-0005-1250-7575
Xiaoling XieHealth Management Center of the Second Affiliated Hospital of Dalian Medical University Dalian Liaoning China.
Yuting SunDepartment of Gastroenterology of the Second Affiliated Hospital of Dalian Medical University Dalian Liaoning China.ORCID 0009-0005-5236-4660
Meng LiHealth Management Center of the Second Affiliated Hospital of Dalian Medical University Dalian Liaoning China.ORCID 0009-0006-3224-8598
Guimin TangHealth Management Center of the Second Affiliated Hospital of Dalian Medical University Dalian Liaoning China.
Song LengHealth Management Center of the Second Affiliated Hospital of Dalian Medical University Dalian Liaoning China.ORCID 0000-0001-6692-9195

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe level of monocyte to high-density lipoprotein ratio (MHR) is associated with cardiovascular diseases. Carotid plaque (CP) is an independent risk factor for cardiovascular diseases. However, evidence for association of MHR with risk of CP is scarce. METHODS AND

resultsThis study involved 5260 participants aged >18 years old from the Dalian health management cohort in 2014 to 2022. The subjects were stratified into 4 groups based on the quartile of the MHR at baseline. Multivariable-adjusted Cox regression models were used to calculate the MHR-associated risk of incident CP. The mean age of the population was 46.14 years and 58.8% (n=3093) of the participants were male. Seven hundred fifty-nine (14.4%) of participants developed new-onset CP. During the follow-up of 9725 person-years, the MHR at quartile 4 group experienced a significantly higher incidence of CP than the MHR at quartile 1 group (56.9 versus 101.5 per 1000 person-years; log-rank

conclusionsElevated MHR was associated with the risk of CP. The assessment and management of MHR is helpful for the early detection of patients with CP and the primary prevention of cardiovascular diseases.

Indexed as

Carotid Artery DiseasesLipoproteins, HDLMonocytesPlaque, AtheroscleroticAdultAgedBiomarkersChinaFemaleHumansIncidenceMaleMiddle AgedRetrospective StudiesRisk AssessmentRisk FactorsBiomarkersLipoproteins, HDLatherosclerosiscarotid plaquecohort studymonocyte to high‐density lipoprotein ratio

Identifiers

PMID39846278
PMCPMC12074780

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.