Evidence map›Paper›PMID 39846199›Full record

ArticleZoological research2025

Functional evolution of thyrotropin-releasing hormone neuropeptides: Insights from an echinoderm.

Yingqiu Zheng, Huachen Liu, Xin Dang, Juan Diego Gaitán-Espitia, Muyan Chen

Abstract read
In one paragraph

Article in Zoological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yingqiu ZhengThe Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao, Shandong 266003, China.
Huachen LiuThe Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao, Shandong 266003, China.
Xin DangThe Swire Institute of Marine Science and School of Biological Sciences, The University of Hong Kong, Hong Kong SAR 999077, China.
Juan Diego Gaitán-EspitiaThe Swire Institute of Marine Science and School of Biological Sciences, The University of Hong Kong, Hong Kong SAR 999077, China. E-mail: jdgaitan@hku.hk.
Muyan ChenThe Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao, Shandong 266003, China. E-mail: chenmuyan@ouc.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Feeding behavior is regulated by a complex network of endogenous neuropeptides. In chordates, this role is suggested to be under the control of diverse factors including thyrotropin-releasing hormone (TRH). However, whether this regulatory activity of TRH is functionally conserved in non-chordate metazoans, and to what extent this process is underpinned by interactions of TRH with other neuropeptides such as cholecystokinin (CCK, known as a satiety signal), remain unclear. This study investigated the TRH signaling system in the echinoderm

Indexed as

Evolution, MolecularNeuropeptidesStichopusThyrotropin-Releasing HormoneAmino Acid SequenceAnimalsCholecystokininFeeding BehaviorGene Expression RegulationReceptors, Thyrotropin-Releasing HormoneCholecystokininNeuropeptidesReceptors, Thyrotropin-Releasing HormoneThyrotropin-Releasing HormoneCholecystokinin (CCK)EchinodermEvolutionFeeding behaviorSatiety signalsThyrotropin-releasing hormone (TRH)

Identifiers

PMID39846199
PMCPMC11890989

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.