Evidence map›Paper›PMID 39846069›Full record

ArticleEuropean heart journal. Digital health2025

Machine learning approaches for risk prediction after percutaneous coronary intervention: a systematic review and meta-analysis.

Ammar Zaka, Daud Mutahar, James Gorcilov, Aashray K Gupta, Joshua G Kovoor, Brandon Stretton, Naim Mridha, Gopal Sivagangabalan, Aravinda Thiagalingam, Clara K Chow and 4 more

Abstract read
In one paragraph

Article in European heart journal. Digital health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ammar ZakaDepartment of Cardiology, Gold Coast University Hospital, 1 Hospital Boulevard, Southport, QLD 4215, Australia.ORCID https://orcid.org/0009-0004-4513-9601
Daud MutaharFaculty of Health Sciences and Medicine, Bond University, 14 University Drive, Robina, QLD 4216, Australia.
James GorcilovFaculty of Health Sciences and Medicine, Bond University, 14 University Drive, Robina, QLD 4216, Australia.
Aashray K GuptaUniversity of Adelaide, Adelaide, SA 5005, Australia.
Joshua G KovoorUniversity of Adelaide, Adelaide, SA 5005, Australia.
Brandon StrettonUniversity of Adelaide, Adelaide, SA 5005, Australia.
Naim MridhaDepartment of Cardiology, The Prince Charles Hospital, 627 Rode Rd, Chermside, QLD 4032, Australia.
Gopal SivagangabalanUniversity of Notre Dame, 128-140 Broadway, Chippendale, NSW 2007, Australia.
Aravinda ThiagalingamDepartment of Cardiology, Westmead Hospital, Cnr Hawkesbury Road and Darcy Rd, Westmead, NSW 2145, Australia.
Clara K ChowDepartment of Cardiology, Westmead Hospital, Cnr Hawkesbury Road and Darcy Rd, Westmead, NSW 2145, Australia.ORCID https://orcid.org/0000-0003-4693-0038
Sarah ZamanDepartment of Cardiology, Westmead Hospital, Cnr Hawkesbury Road and Darcy Rd, Westmead, NSW 2145, Australia.ORCID https://orcid.org/0000-0001-6289-583X
Rohan JayasingheDepartment of Cardiology, Gold Coast University Hospital, 1 Hospital Boulevard, Southport, QLD 4215, Australia.
Pramesh KovoorDepartment of Cardiology, Westmead Hospital, Cnr Hawkesbury Road and Darcy Rd, Westmead, NSW 2145, Australia.ORCID https://orcid.org/0000-0003-2455-5046
Stephen BacchiMassachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Accurate prediction of clinical outcomes following percutaneous coronary intervention (PCI) is essential for mitigating risk and peri-procedural planning. Traditional risk models have demonstrated a modest predictive value. Machine learning (ML) models offer an alternative risk stratification that may provide improved predictive accuracy. Methods and results: This study was reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses, Critical Appraisal and Data Extraction for Systematic Reviews of Prediction Modelling Studies and Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis guidelines. PubMed, EMBASE, Web of Science, and Cochrane databases were searched until 1 November 2023 for studies comparing ML models with traditional statistical methods for event prediction after PCI. The primary outcome was comparative discrimination measured by Conclusion: Machine learning models marginally outperformed traditional risk scores in the discrimination of MACE and major bleeding following PCI. While integration of ML algorithms into electronic healthcare systems has been hypothesized to improve peri-procedural risk stratification, immediate implementation in the clinical setting remains uncertain. Further research is required to overcome methodological and validation limitations.

Indexed as

Artificial intelligenceCoronary artery diseaseMachine learningPercutaneous coronary intervention

Identifiers

PMID39846069
PMCPMC11750198

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.