ArticleHSS journal : the musculoskeletal journal of Hospital for Special Surgery2025
A Pilot Study of the Gut Microbiota in Spine Fusion Surgery Patients.
Article in HSS journal : the musculoskeletal journal of Hospital for Special Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- The Role of Gut Microbiota in Orthopedic Surgery: A Systematic Review.Microorganisms · 2025Review
- Combinatorial characterization of bacterial taxa-driven differences in the microbiome of oyster beds.Sustainable microbiology · 2025Article
- Effects of high dose aspartame-based sweetener on the gut microbiota and bone strength in young and aged mice.JBMR plus · 2024Article
- Effects of long-term high dose aspartame on body mass, bone strength, femoral geometry, and microbiota composition in a young and aged cohort of male and female mice.bioRxiv : the preprint server for biology · 2024Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
Background: The microbiome has been identified as a contributor to bone quality. As skeletal health is critical to success of orthopedic surgery, the gut microbiome may be a modifiable factor associated with postoperative outcomes. For spine fusion surgery in particular, Questions/purposes: We sought to investigate how the composition of the microbiota related to bone health in a focused spinal fusion surgery cohort. Methods: We investigated the composition of the microbiome in a cohort of 31 patients prior to spinal fusion surgery, as well as changes in the microbiome over 6 weeks postoperatively. Preoperative areal bone mineral density (BMD) was measured by dual-energy X-ray absorptiometry. Results: Composition of gut microbiota differed among spinal fusion patients with low bone mass ( Conclusions: Our findings in this small sample suggest there may be a relationship between BMD and composition of the gut microbiome in patients who undergo spinal fusion surgery. Further work is needed to investigate these relationships as well as potential interventions to foster a favorable microbial composition in spinal fusion surgery patients.
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