Evidence map›Paper›PMID 39845796›Full record

ArticleFrontiers in pharmacology2024

Analysis of nanomedicine applications for inflammatory bowel disease: structural and temporal dynamics, research hotspots, and emerging trends.

Hong-Yu Jiang, Bo Shao, Hong-Da Wang, Wen-Qi Zhao, Shao-Hua Ren, Yi-Ni Xu, Tong Liu, Cheng-Lu Sun, Yi-Yi Xiao, Yi-Cheng Li and 6 more

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Current and emerging approaches to manage chronic inflammatory gut disorders.Frontiers in cellular and infection microbiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Hong-Yu Jiang *Department of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Bo Shao *Department of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Hong-Da Wang *Department of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Wen-Qi Zhao *Tianjin Key Laboratory of Precise Vascular Reconstruction and Organ Function Repair, Tianjin, China.
Shao-Hua RenDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Yi-Ni XuDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Tong LiuDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Cheng-Lu SunDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Yi-Yi XiaoDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Yi-Cheng LiDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Qiang ChenDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Peng-Yu ZhaoDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Guang-Mei YangDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Xu LiuDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Yu-Fan RenDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Hao WangDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The application of nanomedicine in inflammatory bowel disease (IBD) has gained significant attention in the recent years. As the field rapidly evolves, analyzing research trends and identifying research hotpots are essential for guiding future advancements, and a comprehensive bibliometric can provide valuable insights. Methods: The current research focused on publications from 2001 to 2024, and was sourced from the Web of Science Core Collection (WoSCC). CiteSpace and VOSviewer were employed to visualize authors, institutions, countries, co-cited references, and keywords, thereby mapping the intellectual structure and identifying emerging trends in the field. Results: The analysis covered 1,518 literature across 447 journals, authored by 9,334 researchers from 5,459 institutions and 287 countries/regions. The global publication numbers exhibited an upward trend, particularly in the last decade, with China leading as the top publishing country and the Chinese Academy of Sciences emerging as the foremost institution. Dr. Xiao Bo is the prominent figure in advanced drug delivery systems. This interdisciplinary field, which spans materials science, pharmacy, and medicine, has seen influential publications mainly concentrated on targeted nanoparticles treatment for IBD. Keyword analysis revealed that current research hotspots include drug delivery, immune cell regulation, antioxidant damage, intestinal microbiota homeostasis, and nanovesicles. Conclusion: This study offers a comprehensive overview of global research landscape, emphasizing the rapid growth and increasing complexity of this field. It identifies key research hotspots and trends, including efforts to enhance the precision, efficacy, and safety of nanomedicine applications. Emerging directions are highlighted as crucial for further progress in this evolving area.

Indexed as

bibliometricsemerging frontiersinflammatory bowel diseasenanomedicineresearch trends

Identifiers

PMID39845796
PMCPMC11750799

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.