Evidence map›Paper›PMID 39845768›Full record

ArticleNature and science of sleep2025

Bimodal Patterns of Locomotor Activity and Sleep in

Arcady A Putilov, Evgeniy G Verevkin, Dmitrii V Petrovskii, Lyudmila P Zakharenko

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature and science of sleep, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Arcady A Putilov *Independent Research Group "biomedical Systems Math-Modeling", Berlin, 12489, Germany.ORCID 0000-0003-2779-9046
Evgeniy G Verevkin *Independent Research Group "biomedical Systems Math-Modeling", Berlin, 12489, Germany.ORCID 0000-0003-2877-1846
Dmitrii V Petrovskii *Department of Insect Genetics, Institute of Cytology and Genetics of the Siberian Branch, the Russian Academy of Sciences, Novosibirsk, 630090, Russia.ORCID 0000-0002-0623-0363
Lyudmila P Zakharenko *Department of Insect Genetics, Institute of Cytology and Genetics of the Siberian Branch, the Russian Academy of Sciences, Novosibirsk, 630090, Russia.ORCID 0000-0002-6341-8522

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Two previously proposed modelling approaches to explain the bimodal pattern of activity and/or sleep in Methods: To obtain typical curves for the simulations, a sample of 4263 individual 24-h curves of locomotor activity and sleep were subjected to principal component analysis. It yielded three principal components, which explained more than 70% of the individual variations in these curves. We calculated the typical curves using scores on the 1 Results: We found that these curves are always characterized by two peaks with varying sizes and timings. They can be fitted by proposing the variation of some of the parameters of the two homeostatic processes reflecting the 24-h rhythmicity of the drive for wake and the 12-h rhythmicity of the drive for sleep. Conclusion: Postulation of two separate circadian oscillators is not necessary to explain the bimodal curves in

Indexed as

bimodal 24-h rhythmfruit flymath-modellingsleep–wake regulating process

Identifiers

PMID39845768
PMCPMC11752963

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.