Evidence map›Paper›PMID 39845615›Full record

ArticleClinical psychological science : a journal of the Association for Psychological Science2024

Comorbidity between internalizing symptoms and disordered eating is primarily driven by genetic influences on emotion regulation in adult female twins.

Megan E Mikhail, S Alexandra Burt, Michael C Neale, Pamela K Keel, Debra K Katzman, Kelly L Klump

Abstract read
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In one paragraph

Article in Clinical psychological science : a journal of the Association for Psychological Science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Megan E MikhailDepartment of Psychology, Michigan State University, USA.
S Alexandra BurtDepartment of Psychology, Michigan State University, USA.
Michael C NealeDepartments of Psychiatry, Human Genetics, and Psychology, Virginia Commonwealth University, USA.
Pamela K KeelDepartment of Psychology, Florida State University, USA.
Debra K KatzmanDepartment of Pediatrics, Hospital for Sick Children and University of Toronto, Canada.
Kelly L KlumpDepartment of Psychology, Michigan State University, USA.

Funding

A Twin Study of exogenous hormone exposure and risk for binge eatingR01MH111715 · NIMH · MICHIGAN STATE UNIVERSITY · PI KLUMP, KELLY L · 2017 to 2021
$4.0M
NIMH NIH HHS R01 MH111715
6 · The paper itself

Abstract

Internalizing (e.g., anxiety, depression) and disordered eating (DE; e.g., binge eating, dietary restraint) are highly comorbid, but the mechanisms underlying their comorbidity remain unknown. This was the first twin study to examine whether their co-occurrence may be driven by genetic and/or environmental influences on emotion regulation (ER; ability to modulate duration/intensity of emotions). Analyses included 688 adult female twins from the MSU Twin Registry. Cholesky decomposition twin models showed comorbidity between dimensionally-modeled internalizing and DE was due to overlapping genetic (

Indexed as

anxietydepressiondisordered eatingEating disordersemotion regulationetiologyinternalizingtwin models

Identifiers

PMID39845615
PMCPMC11753774

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.