Evidence map›Paper›PMID 39845353›Full record

ArticleClinical and experimental hepatology2024

Potential diagnostic value of high b-value computed diffusion-weighted imaging in hepatocellular carcinoma.

Maxime Ablefoni, Theresa Richter, Jakob Leonhardi, Constantin Ehrengut, Gordian Prasse, Matthias Mehdorn, Daniel Seehofer, Anne Kathrin Höhn, Timm Denecke, Hans-Jonas Meyer

Abstract read
In one paragraph

Article in Clinical and experimental hepatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maxime AblefoniDiagnostic and Interventional Radiology, University of Leipzig, Leipzig, Germany.
Theresa RichterDiagnostic and Interventional Radiology, University of Leipzig, Leipzig, Germany.
Jakob LeonhardiDiagnostic and Interventional Radiology, University of Leipzig, Leipzig, Germany.
Constantin EhrengutDiagnostic and Interventional Radiology, University of Leipzig, Leipzig, Germany.
Gordian PrasseDiagnostic and Interventional Radiology, University of Leipzig, Leipzig, Germany.
Matthias MehdornDepartment of Visceral and Transplantation Surgery, University of Leipzig, Leipzig, Germany.
Daniel SeehoferDepartment of Visceral and Transplantation Surgery, University of Leipzig, Leipzig, Germany.
Anne Kathrin HöhnDepartment of Pathology, University of Leipzig, Leipzig, Germany.
Timm DeneckeDiagnostic and Interventional Radiology, University of Leipzig, Leipzig, Germany.
Hans-Jonas MeyerDiagnostic and Interventional Radiology, University of Leipzig, Leipzig, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim of the study: Over the past few years, diffusion-weighted imaging (DWI) has become an increasingly important diagnostic tool in the diagnosis of liver lesions. The objective of the present study was to evaluate the diagnostic benefit of high b-value computed diffusion-weighted imaging (c-DWI) compared with standard DWI in patients with hepatocellular carcinoma (HCC) and whether there is an association with microvascular invasion (MVI). Material and methods: In total, 37 patients with histopathologically confirmed HCC were retrospectively ana-lyzed. DWI was acquired with b-values of 50, 400, and 800 or 1000 s/mm² on a 1.5 T magnetic resonance imaging (MRI) scanner. The c-DWI was calculated using a monoexponential model with high b-values of 1000, 2000, 3000, 4000, and 5000 s/mm². All high b-value c-DWI images were compared to the standard DWI in terms of volume, detectability of hepatic lesions, and image quality. Results: Regarding lesion volume and image quality there were no statistically significant differences between standard and c-DWI. HCC lesions measured on DWI images were statistically significantly larger compared to c-DWI images starting from a b value of 2000 s/mm Conclusions: C-DWI images with high b-values up to b = 1000 s/mm

Indexed as

computed diffusion-weighted imaginghepatocellular carcinomahigh-b-valuemicrovascular invasion

Identifiers

PMID39845353
PMCPMC11748228

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.