Evidence map›Paper›PMID 39845269›Full record

ArticlemicroPublication biology2025

CEP44 and CCDC15 label the spermatozoa proximal and atypical distal centrioles.

Luke Achinger, Briggs Hehl, Jason Suh, Samantha B Schon, Nagalakshmi Nadiminty, Tariq A Shah, Puneet Sindhwani, Tomer Avidor-Reiss

Abstract read
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Article in microPublication biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luke Achinger *University of Toledo, Toledo, Ohio, United States.
Briggs Hehl *University of Toledo, Toledo, Ohio, United States.
Jason Suh *University of Toledo, Toledo, Ohio, United States.
Samantha B SchonUniversity of Michigan-Ann Arbor, Ann Arbor, Michigan, United States.
Nagalakshmi NadimintyUniversity of Toledo, Toledo, Ohio, United States.
Tariq A ShahUniversity of Toledo, Toledo, Ohio, United States.
Puneet SindhwaniUniversity of Toledo, Toledo, Ohio, United States.
Tomer Avidor-ReissThe University of Toledo.

Funding

The Role of Rabbit POC1B inSperm CentriolesR15HD110863 · NICHD · UNIVERSITY OF TOLEDO · PI AVIDOR-REISS, TOMER · 2023 to 2023
$452k
NICHD NIH HHS R15 HD110863
6 · The paper itself

Abstract

The centrosome is a conserved characteristic of eukaryotic and human cells but is highly specialized in reproductive cells. The spermatozoan centrosome includes a slightly modified proximal centriole, an atypical distal centriole, and specialized pericentriolar material, including striated columns and capitellum. We investigated the localization of canonical centriolar proteins CEP44 and CCDC15 in human spermatozoa. We found that CEP44 localizes mainly at the proximal centriole and distal centriole bases relative to centrin. CCDC15 colocalizes with centrin in both the proximal centriole and distal centriole. These findings further our understanding of the spermatozoan centrosome composition.

Identifiers

PMID39845269
PMCPMC11751728

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.