Evidence map›Paper›PMID 39845135›Full record

ArticleNanoscale advances2025

A biocompatible β-cyclodextrin inclusion complex containing natural extracts: a promising antibiofilm agent.

Obaydah Abd Alkader Alabrahim, Mostafa Fytory, Ahmed M Abou-Shanab, Jude Lababidi, Wolfgang Fritzsche, Nagwa El-Badri, Hassan Mohamed El-Said Azzazy

Abstract read
In one paragraph

Article in Nanoscale advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Nanoencapsulation ofRSC advances · 2026
    Article
  3. Review
  4. Article
  5. Improved Bioavailability of Stilbenes fromMolecules (Basel, Switzerland) · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Obaydah Abd Alkader AlabrahimDepartment of Chemistry, School of Sciences & Engineering, The American University in Cairo AUC Avenue, P.O. Box 74 New Cairo 11835 Egypt hazzazy@aucegypt.edu +202 2615 2559.ORCID https://orcid.org/0000-0003-0906-7597
Mostafa FytoryDepartment of Chemistry, School of Sciences & Engineering, The American University in Cairo AUC Avenue, P.O. Box 74 New Cairo 11835 Egypt hazzazy@aucegypt.edu +202 2615 2559.
Ahmed M Abou-ShanabCenter of Excellence for Stem Cells and Regenerative Medicine, Zewail City of Science and Technology Giza 12578 Egypt nelbadri@zewailcity.edu.eg.
Jude LababidiDepartment of Chemistry, School of Sciences & Engineering, The American University in Cairo AUC Avenue, P.O. Box 74 New Cairo 11835 Egypt hazzazy@aucegypt.edu +202 2615 2559.
Wolfgang FritzscheDepartment of Nanobiophotonics, Leibniz Institute of Photonic Technology Jena 07745 Germany.
Nagwa El-BadriCenter of Excellence for Stem Cells and Regenerative Medicine, Zewail City of Science and Technology Giza 12578 Egypt nelbadri@zewailcity.edu.eg.
Hassan Mohamed El-Said AzzazyDepartment of Chemistry, School of Sciences & Engineering, The American University in Cairo AUC Avenue, P.O. Box 74 New Cairo 11835 Egypt hazzazy@aucegypt.edu +202 2615 2559.ORCID https://orcid.org/0000-0003-2047-4222

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biofilms formed by several bacterial strains still pose a significant challenge to healthcare due to their resistance to conventional treatment approaches, including antibiotics. This study explores the potential of loading natural extracts with antimicrobial activities into β-cyclodextrin (βCD) nanoparticles, which are FDA-approved and have superior biocompatibility owing to their cyclic sugar structures, for biofilm eradication. An inclusion complex of βCD carrying

Identifiers

PMID39845135
PMCPMC11748956

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.