Evidence map›Paper›PMID 39845122›Full record

ArticleApplied physics letters2025

Non-contact electroacoustic tomography with optical interferometer for electroporation therapy monitoring.

Yifei Xu, Yuchen Song, Leshan Sun, Zhongping Chen, Liangzhong Xiang

Abstract read
In one paragraph

Article in Applied physics letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yifei XuDepartment of Biomedical Engineering, University of California, Irvine, California 92617, USA.ORCID https://orcid.org/0000-0002-0693-4184
Leshan SunDepartment of Biomedical Engineering, University of California, Irvine, California 92617, USA.ORCID https://orcid.org/0009-0008-1312-2388

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
Phase resolved ARF optical coherence elastography for intravascular imagingR01HL125084 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, ZHONGPING, ZHOU, QIFA · 2014 to 2023
$5.6M
Academic-Industry Partnership for the Translation of a 4D in vivo Dosimetry Approach for Radiation TherapyR37CA240806 · NCI · UNIVERSITY OF OKLAHOMA · PI CHEN, YONG, IVANOV, VASSILI · 2019 to 2025
$2.9M
In vivo Imaging and Quantification of Cilia Beating Dynamics Using Phase-Resolved Optical Imaging TechnologyR01EB030024 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, ZHONGPING, WONG, BRIAN · 2020 to 2024
$2.3M
3D In vivo dosimetry for FLASH proton therapyU01CA288351 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Yong Chen, Lei Ren · 2024 to 2026
$1.8M
Quantitative in vivo dosimetry for radiotherapy using model-based X-ray-induced acoustic computed tomographyR50CA283816 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Prabodh Kumar Pandey · 2024 to 2026
$317k
NCI NIH HHS P30 CA062203NCI NIH HHS R37 CA240806NCI NIH HHS R50 CA283816NCI NIH HHS U01 CA288351NHLBI NIH HHS R01 HL125084NIBIB NIH HHS R01 EB030024
6 · The paper itself

Abstract

Electroacoustic imaging is an imaging modality used to detect electric field energy distribution during electroporation, offering valuable guidance for clinical procedures, particularly in deep tissues. Traditionally, single-element piezoelectric transducers or arrays have been employed for this purpose. However, these piezoelectric sensors are sensitive to electromagnetic interference and require physical contact with the sample through a coupling medium, raising concerns for both clinical and preclinical applications. To overcome these limitations, a multi-channel random quadrature ultrasonics system has been developed, enabling non-contact detection of electroacoustic signals. In this study, we demonstrated that this non-contact technique effectively detects electroacoustic signals, identifies electroporation regions, and reconstructs electric energy distribution, offering a promising approach for monitoring electroporation therapy.

Identifiers

PMID39845122
PMCPMC11748402

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.