Evidence map›Paper›PMID 39845078›Full record

ArticleSurgery in practice and science2022

Comorbid conditions increase the incidence of venous thromboembolism after colorectal surgery.

Roberto G Aru, Sam C Tyagi, Laura M Ebbitt, Jitesh A Patel

Abstract read
In one paragraph

Article in Surgery in practice and science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Roberto G AruUniversity of Kentucky, Lexington, KY, USA.
Sam C TyagiUniversity of Kentucky, Lexington, KY, USA.
Laura M EbbittUniversity of Kentucky, Lexington, KY, USA.
Jitesh A PatelUniversity of Kentucky, Lexington, KY, USA.

Funding

Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2M
NCATS NIH HHS UL1 TR001998
6 · The paper itself

Abstract

Introduction: Colorectal surgery (CRS) patients are at high risk for venous thromboembolism (VTE). The Caprini model elucidates that comorbidities compound to increase VTE risk, but this association in CRS patients remains undefined. We hypothesize that the compounding presence of comorbidities in patients undergoing colorectal resection (CRR) or small bowel resection (SBR) is associated with greater postoperative VTE risk. Methods: This study was a single-institution, retrospective review of patients undergoing CRR and/or SBR from July 2011 to July 2020. Patient demographics, baseline laboratory values, medical comorbidities, and 30-day outcomes were recorded. Incidence of 30-day preoperative or postoperative VTE, including deep venous thrombosis (DVT), pulmonary embolism (PE), portal vein thrombosis (PVT), or inferior vena cava thrombosis (IVCT), were determined. All patients received multimodal in-hospital VTE prophylaxis. After July 2017, patients at high risk for VTE received post-discharge extended chemoprophylaxis. Results: A total of 4354 patients were identified; 129 patients had a postoperative VTE. There was a high incidence of pre-existing comorbidities. In multivariate analysis, acute kidney injury ( Conclusions: Multimorbidity is linearly associated with increased rates of postoperative VTE after CRS surgery. This high-risk population could benefit from novel in-hospital and post-hospital VTE prophylaxis measures.

Indexed as

colorectal surgerydeep venous thrombosisportal vein thrombosispulmonary embolismVenous thromboembolism

Identifiers

PMID39845078
PMCPMC11749960

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.