Evidence map›Paper›PMID 39845074›Full record

ArticleSurgery in practice and science2022

Predictors of mortality in trauma patients with acute respiratory distress syndrome receiving extracorporeal membrane oxygenation.

Miseker Abate, Areg Grigorian, Michael Lekawa, Sebastian Schubl, Matthew Dolich, Patrick T Delaplain, Catherine M Kuza, Jeffry Nahmias

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgery in practice and science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Miseker AbateUniversity of California, Irvine, Department of Surgery, Division of Trauma, Burns and Surgical Critical Care, 333 The City Blvd West, Suite 1600, Orange, CA 92868-3298, USA.
Areg GrigorianUniversity of California, Irvine, Department of Surgery, Division of Trauma, Burns and Surgical Critical Care, 333 The City Blvd West, Suite 1600, Orange, CA 92868-3298, USA.
Michael LekawaUniversity of California, Irvine, Department of Surgery, Division of Trauma, Burns and Surgical Critical Care, 333 The City Blvd West, Suite 1600, Orange, CA 92868-3298, USA.
Sebastian SchublUniversity of California, Irvine, Department of Surgery, Division of Trauma, Burns and Surgical Critical Care, 333 The City Blvd West, Suite 1600, Orange, CA 92868-3298, USA.
Matthew DolichUniversity of California, Irvine, Department of Surgery, Division of Trauma, Burns and Surgical Critical Care, 333 The City Blvd West, Suite 1600, Orange, CA 92868-3298, USA.
Patrick T DelaplainUniversity of California, Irvine, Department of Surgery, Division of Trauma, Burns and Surgical Critical Care, 333 The City Blvd West, Suite 1600, Orange, CA 92868-3298, USA.
Catherine M KuzaDepartment of Anesthesiology, University of Southern California, Los Angeles, CA, USA.
Jeffry NahmiasUniversity of California, Irvine, Department of Surgery, Division of Trauma, Burns and Surgical Critical Care, 333 The City Blvd West, Suite 1600, Orange, CA 92868-3298, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Trauma-related Acute Respiratory Distress Syndrome (TR-ARDS) mortality ranges from 30 to 80%. Extracorporeal membrane oxygenation (ECMO) has demonstrated a survival benefit in select cases of TR-ARDS. In order to provide improved patient selection, we evaluated predictors of mortality in TR-ARDS patients receiving ECMO, hypothesizing age and severe thoracic trauma as risk factors for mortality. Methods: The Trauma Quality Improvement Program (2010-2016) was queried for patients ≥ 18-years-old with TR-ARDS receiving ECMO. Survivors were compared to those who died. A multivariable logistic regression model was used for analysis and included covariates known to increase risk of mortality in trauma patients. Results: From 362 TR-ARDS patients on ECMO, 226 (62.4%) survived and 136 (37.6%) died. Those who died were older (median, 28 vs. 24-years-old, Discussion: Age ≥ 65 years did not appear to increase the risk of mortality in patients with TR-ARDS receiving ECMO. However, those with severe head or thorax injury had more than a two-fold and three-fold increased risk of death, respectively. TR-ARDS patients differ from medical ARDS patients in terms of etiology, age and injuries. Thus, prior pre-ECMO mortality prediction models may lack predictive capability for trauma patients. Future prospective studies are needed to confirm our findings and develop guidelines for utilization of ECMO for trauma patients.

Indexed as

Acute Respiratory Distress SyndromeAge-related mortalityExtracorporeal membrane oxygenationSurgeryTraumaTrauma Quality Improvement Program

Identifiers

PMID39845074
PMCPMC11749176

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.