Evidence map›Paper›PMID 39845018›Full record

ArticleOpen forum infectious diseases2025

Engagement in Preexposure Prophylaxis Care at 1 Year Among Men Who Have Sex With Men Enrolled in the French ANRS PREVENIR Cohort Study.

Geoffroy Liegeon, Lambert Assoumou, Lydie Béniguel, Romain Palich, Gilles Pialoux, Laurence Slama, Laure Surgers, Claudine Duvivier, Michel Ohayon, Hannane Mouhim and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Geoffroy LiegeonAssistance publique-Hôpitaux de Paris, Hôpitaux Saint Louis et Lariboisière, Service des maladies infectieuses, Paris, France.ORCID https://orcid.org/0000-0003-1267-4347
Lambert AssoumouSorbonne Université, INSERM, Institut Pierre Louis d'Épidémiologie et de Santé Publique, Paris, France.
Lydie BéniguelSorbonne Université, INSERM, Institut Pierre Louis d'Épidémiologie et de Santé Publique, Paris, France.
Romain PalichAssistance publique-Hôpitaux de Paris, Hôpital Pitié Salpetrière, Service des maladies infectieuses, Paris, France.ORCID https://orcid.org/0000-0003-0047-0101
Gilles PialouxAssistance publique-Hôpitaux de Paris, Hôpital Tenon, Service des maladies infectieuses, Paris, France.
Laurence SlamaCenter for Research in Epidemiology and StatisticS (CRESS), Inserm, Université Paris Cité, Université Sorbonne Paris Nord and INRAE, F-75004 Paris, France.ORCID https://orcid.org/0000-0002-9871-6036
Laure SurgersSorbonne Université, INSERM, Institut Pierre Louis d'Épidémiologie et de Santé Publique, Paris, France.
Claudine DuvivierAssistance publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Centre d'Infectiologie Necker Pasteur, IHU Imagine, Paris, France.
Michel OhayonCentre 190, Paris, France.
Hannane MouhimCheckpoint, Paris, France.
Juliette PavieAssistance publique-Hôpitaux de Paris, Hôpital Hôtel Dieu, Service des maladies infectieuses, Paris, France.
Duc-Hoan VuSorbonne Université, INSERM, Institut Pierre Louis d'Épidémiologie et de Santé Publique, Paris, France.ORCID https://orcid.org/0009-0009-8785-2460
David MichelsAssociation AIDES et Coalition-plus, Pantin, France.
Mohamed Ben MechliaANRS/Maladies Infectieuses Emergentes, Paris, France.
Bruno SpireAix-Marseille Université, INSERM, Institut de Recherche pour le Développement, Sciences Économique et Sociales de la Santé et Traitement de L'information Médicale, Marseille, France.
Jade GhosnUniversité Paris Cité, Paris, France.ORCID https://orcid.org/0000-0003-2914-959X
Jean-Michel MolinaAssistance publique-Hôpitaux de Paris, Hôpitaux Saint Louis et Lariboisière, Service des maladies infectieuses, Paris, France.
Dominique CostagliolaSorbonne Université, INSERM, Institut Pierre Louis d'Épidémiologie et de Santé Publique, Paris, France.ORCID https://orcid.org/0000-0003-0765-0869

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We evaluated 1-year engagement in pre-exposure prophylaxis (PrEP) care and associated factors among gay, bisexual, and other men who have sex with men (GBMSM) in a large cohort of oral PrEP users in the Paris region, France. Methods: We included in this analysis cisgender GBMSM enrolled in the ANRS PREVENIR cohort study from 3 May 2017 to 28 February 2019. We categorized 1-year PrEP engagement into 4 categories: high (consistent visits, attendance, and prescription refills at months 3, 6, 9, and 12), low (missed visits or no prescription refills), disengagement (PrEP discontinuation), and lost to follow-up. We used a logistic regression model to identify sociodemographic and behavioral factors associated with high engagement in PrEP care. Results: Of 3211 participants, 2685 GBMSM were included in the analysis. At enrollment, participants had a median age of 36 years, with 88% born in Europe and 52.4% already undergoing PrEP. At month 12, 1612 (60.0%) participants met the high engagement definition, 438 (16.3%) exhibited low engagement, 459 (17.1%) disengaged from PrEP care, and 176 (6.6%) were lost to follow-up. In multivariable analysis, high engagement in PrEP care at 1 year was associated with older age ( Conclusions: Younger GBMSM, those born outside Europe, and those who were PrEP naive had lower engagement rates in the cohort, requiring tailored support.

Indexed as

on demandpersistencePrEPretentiontenofovir

Identifiers

PMID39845018
PMCPMC11752861

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.